Topic
Xanthone
About: Xanthone is a research topic. Over the lifetime, 1639 publications have been published within this topic receiving 25870 citations. The topic is also known as: 9-oxo-xanthene & Diphenyline ketone oxide.
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TL;DR: Three new xanthone dimers, named phomoxanthones C–E (1–3), were obtained from the Thai mangrove fungus Phomopsis sp.
13 citations
TL;DR: A new tetraoxygenated xanthone, daphnifolin (1,3,5-trihydroxy-4-methoxyxanthone), along with three other xanthones, were isolated from the stem bark extracts of Mesua daphNifolia and characterized on the basis of 1D and 2D NMR spectral data.
13 citations
TL;DR: A new xanthone glycoside has been isolated from Swertia franchetiana together with five known xanthones and their structures were elucidated on the basis of spectroscopic evidence.
13 citations
Journal Article•
TL;DR: Garcinia mangostana L. (the queen of fruits, mangosteen, family Guttiferae) provided a new xanthone: mangostanaxanthone VII (5), along with four known xanthones: gartanin (3) and γ-mangostin (4).
Abstract: Garcinia mangostana L. (the queen of fruits, mangosteen, family Guttiferae) is a wealthy source of xanthones. The CHCl₃ soluble fraction of the air-dried pericarps of G. mangostana provided a new xanthone: mangostanaxanthone VII (5), along with four known xanthones: mangostanaxanthones I (1) and II (2), gartanin (3) and γ-mangostin (4). The structural verification of these metabolites was achieved by different spectral techniques, including UV, IR, 1D and 2D NMR and HRESIMS. The new metabolite was assessed for cytotoxic potential, using sulforhodamine B (SRB) assay towards the A549 and MCF-7 cancer cell lines. Moreover, its antimicrobial effects were evaluated against various bacterial and fungal strains, using agar disc diffusion assay. Mangostanaxanthone VII showed moderate cytotoxic activity against the A549 and MCF7 cell lines with IC₅₀s 26.1 and 34.8 μM, respectively, compared with doxorubicin (0.74 and 0.41 μM, respectively).
13 citations
TL;DR: In this paper, three types of pyrogallol[4]arenes are cocrystallized with xanthone in isopropanol, acetonitrile, dimethyl sulfoxide, and a mixture of methanol.
Abstract: Cocrystal systems containing pyrogallol[4]arene, xanthone, and solvent molecules are examined and discussed. Three types of pyrogallol[4]arenes are cocrystallized with xanthone in isopropanol, acetonitrile, dimethyl sulfoxide, and a mixture of isopropanol and methanol. It is found that the solvent controls complexation of the xanthone molecule, whereas pyrogallol[4]arene tail length affects cocrystal packing. With a single-solvent system, the xanthone molecule is outside (exo) of the bowl of the pyrogallol[4]arene, but with a two-solvent system, the xanthone molecule is inside (endo) of the bowl of the pyrogallol[4]arene.
13 citations