Topic
Xanthone
About: Xanthone is a research topic. Over the lifetime, 1639 publications have been published within this topic receiving 25870 citations. The topic is also known as: 9-oxo-xanthene & Diphenyline ketone oxide.
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TL;DR: In this paper, the authors proposed a method for the synthesis of xanthone, thioxanthone and anthrone oximes, which are difficult to obtain by conventional dehydrative condensation of corresponding ketones.
Abstract: The method is effective for the synthesis of xanthone, thioxanthone, acridone, and anthrone oximes, which are difficult to obtain by conventional dehydrative condensation of corresponding ketones.
7 citations
TL;DR: In this paper, the chemical study of the orchid Maxillaria picta resulted in the isolation of the bioactive stilbenes phoyunbene B and phoy unbene C. The structures of the compounds were determined by GC-MS, and 1H NMR, 13C NMR spectral methods as well as bidimensional techniques.
Abstract: The chemical study of the orchid Maxillaria picta resulted in the isolation of the bioactive stilbenes phoyunbene B and phoyunbene C, in addition to four phenolic acids, one xanthone, steroidal compounds and two triterpenes. Crude extract, fractions, subfractions and the isolated xanthone were evaluated for anticancer activity against human tumor cell lines and against evolutionary forms of T. cruzi and L. amazonensis. The structures of the compounds were determined by GC-MS, and 1H NMR, 13C NMR spectral methods as well as bidimensional techniques.
7 citations
TL;DR: A detailed chemical study on the ethyl acetate and methanol extracts of the stem bark of Garcinia mangostana resulted in the successful isolation of one new prenylated xanthone, mangaxanthone B, and two known xanthones.
Abstract: A detailed chemical study on the ethyl acetate and methanol extracts of the stem bark of Garcinia mangostana resulted in the successful isolation of one new prenylated xanthone, mangaxanthone B (1), one new benzophenone, mangaphenone (2), and two known xanthones, mangostanin (3) and mangostenol (4). The structures of these compounds were elucidated through analysis of their spectroscopic data obtained using 1D and 2D NMR and MS techniques.
7 citations
TL;DR: In this paper, the authors developed functionalized polyxanthones, poly(azoxanthone-ester)s (PAXEs), with biological activities and heavy metal sorption abilities.
Abstract: The aim of this work was to develop functionalized polyxanthones, poly(azoxanthone-ester)s (PAXEs), with biological activities and heavy metal sorption abilities. For this purpose, at first, new xanthone-based diol moiety was synthesized and then used for polymerization with commercial dicarboxylic acids via polycondensation reaction by Vilsmeier adducts. The monomer and all polymers were characterized by Fourier transform infrared (FTIR) and Nuclear magnetic resonance (NMR) spectroscopies, and the physical properties of these PAXEs including solution viscosity, solubility properties, thermal stability, and thermal behavior were studied. The prepared polyesters showed excellent thermal stability and good solubility in polar aprotic solvents. In addition, evaluation of antioxidant activity of the PAXEs by 2,2-diphenyl-1-picrylhydrazyl assay revealed that synthesized polymers have higher antioxidant activity than xanthone nucleus. Also, evaluation of the antibacterial activities of the diol monomer and polymer showed good antibacterial activity against some bacterial strains (Staphylococcus aureus, Bacillus subtilis, Escherichia coli, and Pseudomonas aeruginosa). The results showed that these PAXEs can be used in pharmaceutical and food industry (food packaging). Furthermore, these functionalized polyesters were utilized for extraction of environmentally harmful metal cations such as Cr (VI), Co (II), Ni (II), Cu (II), Pb (II), and Cd (II) from aqueous solutions. Copyright © 2015 John Wiley & Sons, Ltd.
7 citations
TL;DR: A comprehensive review of xanthone derivatives can be found in this paper, where a breadth of synthetic strategies for xanthones derivatives have been developed, including the use of ytterbium, palladium, ruthenium, copper, and chromen-4-ones as building blocks.
Abstract: Many xanthone structures show promising biological activities. Accordingly, a breadth of synthetic strategies toward xanthone derivatives have been developed. This review surveys these methods published from 2013 to 2019, and in an integrated manner details the biological activities of key xanthone structures. The review highlights the synthesis of xanthones via the classical and the modified Grover, Shah, and Shah reaction; the use of ytterbium, palladium, ruthenium, copper catalysis; the use of chromen-4-ones as building blocks; the use of the Friedel–Crafts reaction; Ullmann-ether coupling; metal-free oxidative coupling; intermolecular and intramolecular couplings; xanthone synthesis via the intermolecular Diels–Alder reaction; a novel decarboxylative aminocatalytic strategy; use of the Michael reaction, and the use of the Knoevenagel–Michael, Michael/Michael, Michael/Henry cycloadditions; and [4+2] cycloaddition.
7 citations