Topic
Xanthone
About: Xanthone is a research topic. Over the lifetime, 1639 publications have been published within this topic receiving 25870 citations. The topic is also known as: 9-oxo-xanthene & Diphenyline ketone oxide.
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TL;DR: It was proved that the presence of 3-OH group in the molecule is crucial for its biological activity, while the presenceof substituents at C-5 and C-6 may also be beneficial.
7 citations
01 Jan 2012
TL;DR: The data indicate the prokinetic action of mangiferin can stimulate the normal GIT and also overcome the drug-induced transit delay, via a cholinergic physiological mechanism.
7 citations
TL;DR: A novel 1,4-oxazine-xanthone derivative, fusarioxazin, possessed a significant antibacterial activity towards S. aureus and B. cereus and displayed a promising cytotoxic effect toward HCT-116, MCF-7, and A549.
7 citations
TL;DR: In this article, six new xanthone dimers, diaporxanthones A-F (1-6), and an unusual Xanthone monomer diPORxanthone G (7), in addition to seven known analogues (8-14), were isolated and identified from endophytic Diaporthe goulteri L17 harbored in the fruits of the salt-tolerant plant Vitex trifolia.
Abstract: Six new xanthone dimers, diaporxanthones A-F (1-6), and an unusual xanthone monomer diaporxanthone G (7), in addition to seven known analogues (8-14), were isolated and identified from endophytic Diaporthe goulteri L17 harbored in the fruits of the salt-tolerant plant Vitex trifolia. The chemical structures of these metabolites were elucidated on the basis of nuclear magnetic resonance, high-resolution electrospray ionization mass spectrometry, and reported data in the literature. Their absolute configurations were established by single-crystal X-ray diffraction analysis together with time-dependent density functional theory electronic circular dichroism calculations. Among these compounds, compounds 1 and 6 exhibited moderate antifungal activities against Nectria sp. and Colletotrichum musae and compound 4 showed significant cytotoxicity against all selected five cancer cell lines.
7 citations
TL;DR: A new xanthone (1) was isolated together with nine known xanthones (2 - 10, 12) and a known benzofuran (11) from the stems of Garcinia kola Heckel (Guttiferae) collected in Nigeria and their structures were characterized on the basis of spectroscopic and chemical evidence.
Abstract: A new xanthone (1) was isolated together with nine known xanthones (2 - 10, 12) and a known benzofuran (11) from the stems of Garcinia kola Heckel (Guttiferae) collected in Nigeria and their structures were characterized on the basis of spectroscopic and chemical evidence.
7 citations