Xanthone

About: Xanthone is a research topic. Over the lifetime, 1639 publications have been published within this topic receiving 25870 citations. The topic is also known as: 9-oxo-xanthene & Diphenyline ketone oxide.

butenyl)-3-(2"-methyl-3"-butenyl)pyrano(2,3- a)xanthen-12(2H)-one from the Stem Bark of Calophyllum pseudomole

Abstract: 5,9,11-Trihydroxy-2,2-dimethyl-10-(3 0 -methyl-2 0 -butenyl)-3-(2”-methyl-3”-butenyl)-pyrano[2,3-a]xanthen-12(2H)-one ( 1 ) was isolated from the stem bark of Calophyllum pseudomole.The structure of 1 was established by spectroscopic analysis which included UV, IR, HRESIMS andNMR experiments. Keywords: 5,9,11-trihydroxy-2,2-dimethyl-10-(3 0 -methyl-2 0 -butenyl)-3-(2”-methyl-3”butenyl)-pyrano[2,3-a]xanthen-12(2H)-one; xanthone; Calophyllum pseudomole 1. Introduction The Calophyllum genus (Clusiaceae) comprises more than 180 species found mainly in SoutheastAsia. This genus has been shown to produce a number of secondary metabolites, particularlyxanthones [1–3], coumarins [4–6], chromanone acids [7–9], and flavonoids [10]. In Indonesia, the localname of Calophyllum is ‘bitangor’ [11].Herein, we report the isolation and structural elucidation of a new isoprenylated xanthone,5,9,11-trihydroxy-2,2-dimethyl-10-(3 0 -methyl-2 0 -butenyl)-3-(2”-methyl-3”-butenyl)-pyrano[2,3-a]xanthen-12(2H)-one (

Synthetic studies of mangostin derivatives with an inhibitory activity on PDGF-induced human aortic smooth cells proliferation

Abstract: The mangostin derivatives 3-10, were synthesized by halogenation, electrochemical oxidation, and mCPBA oxidation of α- and γ-mangostins (1, 2). Among them, the hydroxyl 9 and the benzopyran 10 derivatives produced by mCPBA, showed remarkable antiproliferative activities against human aortic smooth muscle cells (HASMC) induced by platelet-derived growth factor (PDGF).

[Studies on chemical constituents of Polygala arillata buch-ham].

Abstract: Two new compounds were isolated from the roots of Polygala arillata Buch Ham.. On the basis of chemical reactions and spectral (UV, IR, MS, 1HNMR, DIFNOE, 13 CNMR) analysis,they were identified as 1,3 dihydroxy 2 methoxyxanthone(I) and 7 hydroxy 1 methoxy 2,3 methylenedioxyxanthone(II). Pharmacological study indicated that I and II have inhibitory effect on aldose reductase activity.

Dibenzo-six-membered-ring substituted compound with xanthone as nucleus and application thereof

Abstract: The invention discloses a compound based on xanthone and application thereof. The compound uses xanthone as a mother nucleus which is connected with a heteroaromatic group, so symmetry of molecules is destroyed, aggregation of molecules is prevented, and good film forming ability is obtained. The compound is used as a luminescent layer material for an organic light-emitting diode (OLED); and an OLED device using the compound has good photoelectric performance and can meet requirements of panel manufacturers.

Health and Wellness Product from Mangosteen (Garciniamangostana L.) Rind: Bioactive Potentials

Abstract: Mangosteen rind (MSR) (Garcinia mangostana L.) is a predominant component of the fruit contributing to 62% of the whole fruit. However, utilization of the same for the preparation of health products was not explored due to its sensorially less acceptable parameters. Differential extraction in different polarity solvents of MSR was done and evaluated their acceptability for product preparation. Current study thus is a detailed investigation on bioactivity profiling of MSR fraction and utilization of the same for health product preparation. Among various extracts, 70% ethanol (70%AE) yielded the maximum (15g/100g). Xanthone:Phenolic ratio was 1: 2.8, in 70%AE as opposed to hot water extract – HWE and 50% AE, which contained Xanthone:Phenolic ratio of 1:1.4/5. Higher the phenolic content obviously reduces the bitterness of Xanthones. 70% AE contained phenolics 60.08± 0.213 mg/g and xanthones 22.56± 0.317 mg/g. HPLC analysis revealed a spectrum of phenolic acids such as gallic, chlorogenic, caffeic, epicatechin, catechin and ferulic acids at various levels. Potent Free Radical Scavenging (FRS) activity, cytoprotectivity, DNA protectivity, H+K+ATPase inhibitory (PPAI) activities were observed in 70% AE. Gallic/tannic acid appear to contribute to antioxidant activity; while ferulic acid was responsible for PPAI activity in 70%AE. Among xanthones, although