Topic
Xanthone
About: Xanthone is a research topic. Over the lifetime, 1639 publications have been published within this topic receiving 25870 citations. The topic is also known as: 9-oxo-xanthene & Diphenyline ketone oxide.
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TL;DR: In this paper, a heat-pulse modulation technique has been applied to the phosphorescence study of xanthone in n -pentane at 1.5 and 4.2 K.
5 citations
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TL;DR: In this article, a new xanthone (2,7dihydroxyxanthone) was isolated from the aerial parts (stems and bark) of Mammea acuminata.
Abstract: From the stem of Poeciloneuron pauciflorum , two new xanthones (1,6-dihydroxy-7-methoxyxanthone and 1,6-dihydroxy-7-methoxyxanthone 6-O-β- d -glucoside ) in addition to 12 known compounds (1,5-dihydroxy-, 1,5-dihydroxy-3-methoxy-, 1,7-dihydroxy-, 1-hydroxy-7-methoxy-, 2-methoxy-, 4-methoxy-, 1,4,5-trihydroxy-, 1,3,5-trihydroxy-, 1,3,6-trihydroxy-7-methoxy-, 1,3,7-trihydroxy-, 3-hydroxy-2-methoxyxanthone and (−)-epicatechin) were isolated. From the aerial parts (stems and bark) of Mammea acuminata , a new xanthone (2,7-dihydroxyxanthone) was isolated in addition to two known xanthones (1,5-dihydroxy- and 5-hydroxy-1-methoxyxanthone) and (−)-epicatechin. The structures were established by spectral analysis and total synthesis in case of 1,6-dihydroxy-7-methoxyxanthone.
5 citations
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TL;DR: In this paper, the polarized infrared spectrum of xanthone embedded in a stretched polyethylene film has been measured and the symmetry assignments derived from the polarization data are in excellent agreement with the predictions of scaled B3-LYP/6-31G(d) density functional theory calculations.
5 citations
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TL;DR: In this paper, a series of 2-substituted 1,4-dihydropyridines with a xanthone backbone was prepared. The compounds were evaluated for inotropic, chronotropic and calcium antagonist properties.
Abstract: A series of 2-substituted 1,4-dihydropyridines with a xanthone backbone was prepared. The compounds were evaluated for inotropic, chronotropic and calcium antagonist properties.
5 citations
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TL;DR: The chloroform extract, when tested against RAW264.7 cells for anti-inflammatory potentials, exhibited the most promising activity with an IC50 value of 14.81±0.04 µg/mL compared to moderate activities shown by the ethyl acetate and n-hexane extracts.
Abstract: Repeated separation and purification of fractions from the crude chloroform extract of Calophyllum inophyllum via column chromatography afforded five known xanthone caloxanthones A, B, C, macluraxanthone and pyranojacareubin. Structural elucidations and determination of the isolated compounds were supported by spectral analyses obtained by subjecting the compounds to various spectroscopic techniques. The chloroform extract, when tested against RAW264.7 cells for anti-inflammatory potentials, exhibited the most promising activity with an IC50 value of 14.81±0.04 µg/mL compared to moderate activities shown by the ethyl acetate and n-hexane extracts. Antimicrobial tests showed that the n-hexane and chloroform extracts acted moderately against Staphylococcus epidermidis S273 and Bacillus subtilis B145.
5 citations