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Xanthone

About: Xanthone is a research topic. Over the lifetime, 1639 publications have been published within this topic receiving 25870 citations. The topic is also known as: 9-oxo-xanthene & Diphenyline ketone oxide.


Papers
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Journal ArticleDOI
TL;DR: The binary system of xanthone and thioxanthone has been explored in this article, showing that two solid solutions (formed based on Xanthone parent structures, respectively) exist for this system.
Abstract: The binary system of xanthone–thioxanthone has been explored, showing that two solid solutions (formed based on xanthone and thioxanthone parent structures, respectively) exist for this system. One...

4 citations

Journal ArticleDOI
TL;DR: In this article , the structures of the new compounds were established on the basis of spectroscopic methods, including high-resolution electrospray ionization mass spectrometry and one-and two-dimensional nuclear magnetic resonance.
Abstract: Eight new polyketides, including three dimeric benzophenones, named dipleosporones A-C (1-3), three benzophenones (4-6), one xanthone (7), and one phenylbenzoate (8), along with seven known polyketides (9-15) were isolated from the fungus Pleosporales sp. YY-4. The structures of the new compounds were established on the basis of spectroscopic methods, including high-resolution electrospray ionization mass spectrometry and one- and two-dimensional nuclear magnetic resonance. This is the first report of a benzophenone dimer connection via a C bridge from natural sources. An anti-inflammatory assay indicated that the dimeric benzophenones (1-3) inhibited lipopolysaccharide-induced NO production in RAW 264.7 cells, with half-maximal inhibitory concentration (IC50) values ranging from 8.8 to 18.1 μM, being more potent than the positive control, dexamethasone (IC50 = 22.2 μM).

4 citations

Patent
22 Mar 2012
TL;DR: In this article, an a-mangosteen diester represented by general formula (1): (in the formula, R1 represents the residue after a hydroxyl group is removed from a C8-14 medium chain triglyceride), and an anticancer agent or metastasis inhibiting agent including said compound as the active component thereof.
Abstract: Provided is a novel compound having excellent anticancer activity and metastasis inhibition activity. An a-mangosteen diester represented by general formula (1): (in the formula, R1 represents the residue after a hydroxyl group is removed from a C8-14 medium chain triglyceride), and an anticancer agent or metastasis inhibiting agent including said compound as the active component thereof.

3 citations

Journal Article
TL;DR: By appropriate superimposing of fenofibrate and fen ofibric acid molecules, two xanthone derivatives (closed models) may be obtained and very promising for further studies is the chlorine-free 3-isomer (3e).
Abstract: By appropriate superimposing of fenofibrate and fenofibric acid molecules, two xanthone derivatives (closed models) may be obtained. These compounds as well as their four chlorine-free isomers were prepared and tested on adrenaline- and theophylline-induced lipolysis in rat fat cells in comparison with ethyl 2-(4-chlorophenoxy)-2-methylpropionate (clofibrate). Some of these new derivatives besides being good inhibitors of adrenaline effect, as clofibrate is, were also very active in reducing theophylline-induced lipolysis. Very promising for further studies is the chlorine-free 3-isomer (3e). The possible difference in the action mechanism of these compounds as compared with clofibrate and the structure-activity relationships are briefly discussed.

3 citations

Journal ArticleDOI
TL;DR: In this article, two prenylated anthraquinones, laurenquinone A (1) and B (2), were isolated from the seeds of Vismia laurentii together with four known compounds; xanthone V 1 (3), physcion (4), 3-geranyloxyemodin anthrone (5) and friedelin (6).
Abstract: Two new prenylated anthraquinones, laurenquinone A (1) and B (2) were isolated from the seeds of Vismia laurentii together with four known compounds; xanthone V 1 (3), physcion (4), 3-geranyloxyemodin anthrone (5) and friedelin (6). The structures of the new metabolites were determined with the help of spectroscopic data including extensive 2D-NMR spectroscopy. The known compounds were identified by comparison of their physical and spectroscopic data with those reported in the literature. Compounds 1, 4 and 5 exhibited moderate algicidal activity against Chlorella fusca and 3 showed moderate activity against the gram-positive bacterium Bacillus megaterium.

3 citations


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Performance
Metrics
No. of papers in the topic in previous years
YearPapers
202347
202296
202146
202054
201949
201872