Topic
Xanthone
About: Xanthone is a research topic. Over the lifetime, 1639 publications have been published within this topic receiving 25870 citations. The topic is also known as: 9-oxo-xanthene & Diphenyline ketone oxide.
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Journal Article•
TL;DR: Ten compounds were isolated and purified from cell suspension cultures of Cudrania tricuspidata with silica-gel column chromatography, semi-preparative HPLC and Sephadex LH-20, and compound 1 was a xanthone which was isolated from the plant for the first time.
Abstract: Ten compounds were isolated and purified from cell suspension cultures of Cudrania tricuspidata with silica-gel column chromatography, semi-preparative HPLC and Sephadex LH-20. On the base of their physicochemical properties and spectral data, their structures were identified as 1, 3, 5-trihydroxy4-(3, 3-dimethylallyl) xanthone (1), wighteone (2), 6-prenylapigenin (3), licoflavone C(4), cudraflavanone C(5), erythrivarone A (6), derrone (7), carthamidin (8), genistein (9) and aromadendrin (10). Among them, compounds 2-10 were flavonoids, and compound 1 was a xanthone which was isolated from the plant for the first time.
3 citations
Patent•
10 Sep 2012TL;DR: In this paper, the present invention relates to xanthone analogs and such compounds may be used in the treatment of bacterial infections, such as MRSA and MRSA infection.
Abstract: The present invention relates to xanthone analogs. Such compounds may be used in the treatment of bacterial infections.
3 citations
TL;DR: In this paper, the crystal structure of 1-dimesitylboron-4-(9-xanthylium)-phenylene (1) + as a tetrafluoroborate salt has been determined.
Abstract: Reaction of 4-(lithiophenyl)dimesitylborane with xanthone followed by reaction of the resulting alcohol with HBF4 affords the cation 1-dimesitylboron-4-(9-xanthylium)-phenylene (1) + as a tetrafluoroborate salt. This salt has been fully characterized and its crystal structure determined. Cation (1) + can be reduced to produce a persistent radical that has been studied by EPR and whose reaction with dioxygen affords a peroxo derivative.
3 citations
TL;DR: Vaccaxanthone, a 7-carboxy-1,3,5,8-tetraoxygenated xanthone has been isolated from Saponaria vaccaria as mentioned in this paper.
Abstract: Vaccaxanthone, a novel 7-carboxy-1,3,5,8-tetraoxygenated xanthone has been isolated from Saponaria vaccaria. its structure has been established from spectroscopic data including uv, ir, high resolution-ms, 1 H- and 13 C-nmr as 1,8-dihydroxy-3,5-dimethoxyxanthone-7-carboxylic acid
3 citations
17 Nov 2016
TL;DR: This study investigates the toxicity level of xanthone in zebrafish embryo to for future reference on other animal model and found it did not harm the embryos and showed 100% of survival.
Abstract: Xanthone is a chemical compound identified in mangosteen pericarp. A previous study showed that xanthone has anti-proliferating effect on cancer cells. In this study we investigate the toxicity level of xanthone in zebrafish embryo to for future reference on other animal model. We employed Fish Embryo Toxicity (FET) assay to determine the toxicity level of different concentrations of xanthone. Embryos were observed at 24, 48 and 72 hours post fertilization (hpf) under microscope at 4× magnification. The extract showed toxicity effect on embryo at concentrations of 250, 125 and 62.5 µg/mL. Concentrations at 15.63, 7.81 and 3.91 µg / mL of xanthone did not harm the embryos and showed 100% of survival.
3 citations