Topic
Xanthone
About: Xanthone is a research topic. Over the lifetime, 1639 publications have been published within this topic receiving 25870 citations. The topic is also known as: 9-oxo-xanthene & Diphenyline ketone oxide.
Papers published on a yearly basis
Papers
More filters
TL;DR: In this paper, the ozonation of xanthydrol was studied using an oxygen stream, which gave singlet oxygen, water and xanthone accompanied by autoxidation.
Abstract: The ozonation of xanthene was studied using an oxygen stream. Ozone attacks the methylene group of xanthene via a 1,3-dipolar insertion reaction to give the hydrotrioxide intermediate, followed by a loss of singlet oxygen to form xanthydrol. The ozonation of xanthydrol gave singlet oxygen, water and xanthone accompanied by autoxidation.
2 citations
TL;DR: Using various chromatographic methods, two new sucrose esters, karensucrose A (1) and karenssucrose B (2), one new xanthone, Karenxanthone (7) along with eight known compounds, 3-(E)-3,4,5-trimethoxycinnamoyl-6′-benzoylsucrose (3), tricornose B (4), glomeratose C (5), tenuifoliside C (6), 1,7-dihyd
2 citations
TL;DR: In this article, a phytochemical investigation to obtain intestine motility inhibitor resulted in the isolation of one new xanthone glycoside, gentixanthonoside A (1), along with nine tetrahydroxanthones, 1,3,5R,8S-tetrahydroxy-5,6,7,8-Tetrahyroxanthone (3), amarellin E (4), amarelin F (5), swertiachoside B (6), amellellin D (7
2 citations
TL;DR: In this paper, the interaction of Fe-NO2At-α-mangostin complex compound against FAS receptor using molecular dynamics software was found out, and the model of molecular dynamic result could be used as a model for the production of 68Ga-α mangostins in radiopharmaceutical.
Abstract: α-mangostin is a xanthone compound isolated from mangosteen pericarp. It is known as an anticancer through induction of apoptotic process by inhibiting fatty acid synthase (FAS) receptor. α-mangostin is a potentially useful ligand for diagnostic purposes in the form of complexes with a radionuclide such as68Gallium (68Ga). Unfortunately, α-mangostin could not be directly labeled with radionuclides. In order to be labeled, a chelator such as 1,4,7-triazacyclononane-1,4,7-triacetic acid (NOTA), a derivative (NO2At), is required. The aim of this study was to find out the interaction of Fe-NO2At-α-mangostin complex compound against FAS receptor using molecular dynamics software. Both the metals have similar chemical characteristics. The results showed a strong interaction between Fe-NO2At-α-mangostin complex compound and FAS receptor. The molecular dynamic showed the complex compound Fe-NO2At-α-mangostin in FAS-KS which produced a bond-free energy values (ΔG) of - 96.7 kcal/mol, forming hydrogen bonds with amino acid residues Glu 115 and Ser 114. The model of molecular dynamic result could be used as a model for the production of 68Ga-α-mangostin in radiopharmaceutical.
2 citations
Patent•
23 Nov 2018
TL;DR: The Xanthone fluorochrome has the following structure general formulas I, II, III and IV shown in the description, wherein R1, R2, R3 and R4 are respectively selected from hydrogen, halogen, hydroxyl, NH2, sulfydryl, cyano-group, nitryl and N,N-bis-C1-4 alkyl amino group.
Abstract: The invention provides xanthone fluorochrome and application therefore to design synthesis of a fluorescence probe. The Xanthone fluorochrome has the following structure general formulas I, II, III and IV shown in the description, wherein R1, R2, R3 and R4 are respectively selected from hydrogen, halogen, hydroxyl, NH2, sulfydryl, cyano-group, nitryl, N,N-bis-C1-4 alkyl amino group, aldehyde group, carboxyl, amido, sulfoamido, C5-10 aryl, C2-8 heterocyclic aryl, C1-6 alkyl, boric acid, boronic acid pinacol ester and OR (wherein R is C1-4 saturated alkyls or unsaturated alkyls).
2 citations