scispace - formally typeset
Search or ask a question
Topic

Xanthone

About: Xanthone is a research topic. Over the lifetime, 1639 publications have been published within this topic receiving 25870 citations. The topic is also known as: 9-oxo-xanthene & Diphenyline ketone oxide.


Papers
More filters
Journal ArticleDOI
01 Feb 2017
TL;DR: In this paper, the preparation of inclusion complex with xanthone and measurement of antibacterial activity against Escherichia coli have been performed using Fourier Transform Infrared Spectroscopy and H Nuclear Magnetic Resonance (H-NMR).
Abstract: The preparation of inclusion complex sulfonatocalix[4]arene (SC[4]A) with xanthone and measurement of antibacterial activity against Escherichia coli have been performed. Analysis of the structure of inclusion complex between SC[4]A and xanthone was investigated by using Fourier Transform Infrared Spectroscopy (FT-IR) and H Nuclear Magnetic Resonance (H-NMR). The solubility of the product in water was examined. Surface area and porous determination were analyzed by Surface Area Analyzer (SAA). Antibacterial activity test was performed for 0, 3, 6, 9, 12, and 24 hours. The results showed that antibacterial activity of the complex of xanthone SC[4]An against Escherichia coli was higher than that of xanthone it self.

1 citations

Journal ArticleDOI
TL;DR: In this article , an unprecedented approach to the xanthone scaffold from cyclohexyl(2-hydroxyphenyl)methanone via dehydrogenative cyclization and a successive aromatization cascade is reported.

1 citations

Patent
19 Jan 2018
TL;DR: In this paper, a Xanthone-NO donor compound and a preparation method thereof and application in preparation of an antitumor drug are presented. But the preparation method is not described.
Abstract: The invention belongs to the technical field of antitumor drugs and discloses a Xanthone-NO donor compound and a preparation method thereof and application in preparation of an antitumor drug. The Xanthone-NO donor compound has a structure as shown in the formula I in the specification. In the formula I, R1, R2 and R3 are the same or different (are respectively H, OH, Cl, Br or F); and n= 2-8. Thepreparation method comprises the following steps: xanthones is prepared from substituted salicylic acid and phloroglucinol; then, xanthones react with 1,n-dibromosubstituted alkane to prepare 3-O-bromoalkyl xanthone; and finally bromine conversion is carried out. The compound of the invention has excellent in vitro tumor cell proliferation inhibitory activity and can conduct multi-target induction of cancer cell apoptosis. Thus, the compound can be applied in the preparation of an antitumor drug, especially drugs for multi-target therapy of cancers and drugs for therapy of tumors caused by nitric oxide anomaly.

1 citations

Patent
06 Sep 2017
TL;DR: In this article, a composition for preventing vascular calcification, containing at least one type of mangostin xanthone compounds including -mangostin, gartanin, and gartin, was proposed.
Abstract: The present invention relates to a composition for preventing vascular calcification, containing, as an active ingredient, at least one type of mangostin xanthone compounds including -mangostin, -mangostin, and gartanin. Particularly, by regulating expression of genes associated with vascular calcification such as Runt-related transcription factor 2 (RUNX2), osteopontin, and sm22a, it is possible to prevent vascular calcification.

1 citations


Network Information
Related Topics (5)
Triterpene
4.1K papers, 81.1K citations
88% related
Absolute configuration
7.8K papers, 124.7K citations
87% related
Glycoside
4.6K papers, 80.8K citations
87% related
Chalcone
4.4K papers, 74.7K citations
86% related
Apigenin
2.3K papers, 88.1K citations
84% related
Performance
Metrics
No. of papers in the topic in previous years
YearPapers
202347
202296
202146
202054
201949
201872