Topic
Xylopia aethiopica
About: Xylopia aethiopica is a research topic. Over the lifetime, 347 publications have been published within this topic receiving 5511 citations.
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TL;DR: The results of a preliminary antimicrobial screening of the methanol extracts of Aframomum melegueta, Piper guineense, Xylopia aethiopica, Zingiber officinale, medicinal plants of Ghana, are reported.
128 citations
TL;DR: Five essential oils extracted from the Cameroonian plants were evaluated in regard to their anti-plasmodial activity against the W2 strain of Plasmodium falciparum, and the most effective was the oil of Hexalobus crispiflorus, with an IC50 of 2 microg/ml.
127 citations
TL;DR: Hot water extracts obtained from leaf and seed of uda and Ginger were found to be fungitoxic against the fungi and suppressed the growth of these fungi in culture and reduced rot development in yam tubers.
Abstract: Investigation was carried out to test the potency of some plant extracts for the control of yam tuber rot caused by Fusarium oxysporum, Aspergillus niger and Aspergillus flavus. Hot water extracts were obtained from leaf and seed of uda (Xylopia aethiopica) and Ginger (Zinigiber officinale), and were found to be fungitoxic against the fungi. The extracts of suppressed the growth of these fungi in culture and reduced rot development in yam tubers.
126 citations
TL;DR: Six ent-kaurane diterpenes in the hexane extract of Xylopia aethiopica fruits and an aqueous methanol extract of the seeds were studied for termite antifeedant activity against workers of the subterranean termite, Reticulitermes speratus.
114 citations
TL;DR: The extract demonstrated good hypoglycaemic effects by lowering the plasma sugar level and also had some beneficial and reduction effects on cardiovascular risk factors and subacute results revealed a tendency to cause kidney problems on a long-term use.
Abstract: The present study was carried out to evaluate acute and subacute toxicity of a hydroalcoholic extract of a mixture (1:1) of A. congensis bark and X. aethiopica fruits used locally in the treatment of diabetes. Acute toxicity of the extract was evaluated in Swiss albino mice. The animals were fed with the hydroalcoholic extract between the doses of 1.0 to 20.0 g/kg body weight and were observed continuously for the first 4 h and for every hour for the next 24 h, then 6 hourly for 48 h. Wistar rats were also fed with different doses of the extract for 30 days and effects on biochemical parameters evaluated (subacute toxicity model). The LD50 of the extract was found to be above 20.0 g/Kg body weight. There was reduction in the plasma glucose and low-density lipoprotein (LDL)-cholesterol levels, and increase in high-density lipoprotein (HDL)-cholesterol level in the treated animals. A significant increase in the body weight was observed for groups treated with lower doses of the extract while groups treat with higher doses showed no significant weight increase. Aspartate aminotransferases (AST) and alanine aminotransferases (ALT) levels were not affected at lower doses of the extract but there was increase in creatinine levels in all the treated animals. The extract demonstrated good hypoglycaemic effects by lowering the plasma sugar level and also had some beneficial and reduction effects on cardiovascular risk factors. There was no evidence of drug-induced symptoms or death at all the doses of the extract administered in acute study but subacute results revealed a tendency to cause kidney problems on a long-term use.
111 citations