Xylopia aethiopica

About: Xylopia aethiopica is a research topic. Over the lifetime, 347 publications have been published within this topic receiving 5511 citations.

Composition and Radical Scavenging Activity of Essential Oil from Xylopia aethiopica: A New Chemotype Grown in Nigeria

Abstract: Despite its use in traditional medicines, studies on the radical scavenging activity of the essential oils from Xylopia aethopica from Nigeria have not been widely reported in literature. Thus, in this work, fresh fruits of Xylopia aethopica were air dried, ground and extracted through hydro-distillation using Clevenger-type distillation apparatus. The essential oil was analyzed using Gas Chromatographic/Flame Ionization Detection (GC/FID) Technique and confirmed by gas chromatographic/mass spectrometric (GC/MS) analysis. The radical scavenging activity of the essential oil was evaluated in comparison with butylated hydroxylanisole (BHA) through 1,1-Diphenyl-2-picrylhydrazyl (DPPH) scavenging assay. A total of Forty-five compounds were detected through the GC/FID and GC/MS analyses of the essential oil of Xylopia aethopica. The major constituents of the essential oil were β-pinene (55.15%), α-thujene (9.23%) and α-eudesmol (8.61%) and α-pinene (6.77%). Other notable constituents were 1, 8-cineole (6.13%), ethyl cinnamate (5.83%) and elemol (5.17%). The methanolic solution of the essential oil showed concentration-dependent scavenging activity on 1,1-Diphenyl-2-Picrylhydrazyl (DPPH) radical. The results of the Scavenging effect of the Xylopia aethopica essential oil compared well with the activity of the commercial radical scavenging agent, Butylated hydroxylanisole (BHA) and this suggests possible uses of the essential oil as sources of natural antioxidants. Data were analyzed using R statistical software.

Cosmetic composition based on alpha-2 adrenergic receptor antagonist

Abstract: Use of Xylopia aethiopica as an alpha-2 adrenergic receptor antagonist in the preparation of a composition for topical application as well as said compositions. The topical application of such a composition is likely to stop the local accumulation of fat and thus improve the aesthetic appearance of the skin. Such a composition can also be used to massage the skin of the stressed man's body.

Collaborative effects of some anti-diabetic plants on the liver marker enzymes of diabetic rats

Abstract: The leaves of Psidium guajava, Anacardium occidentale, Eucalyptus globulus and fruits of Xylopia aethiopica are used in the management of diabetes mellitus. The phytochemical constituents as well as the acute toxicity of the combined chloroform extracts (A. occidentale + E. globulus and P. guajava + X. aethiopica) and their effects (at graded doses of 100 and 250 mg/kg body weight each) on the activities of alanine aminotransferase (ALT), aspartate aminotransferase (AST) and alkaline phosphatase (ALP) were therefore, assayed in diabetic and normal rats using standard methods. The phytochemical analyses of the four extracts showed the presence of flavonoids, terpenoids and fats and oil in all of them. Each of the combined extract was found to be non-toxic even at a dose as high as 5000 mg/kg body weight. The combined extracts at the tested doses significantly (p<0.05) and dose-dependently decreased the activities of ALT, AST and ALP. The effects of the combined extracts (especially 250 mg/kg body weight of P. guajava + X. aethiopica) were better than that of the standard anti-diabetic drug [glibenclamide (5 mg/kg body weight)]. The results generally indicate that the combined chloroform extracts of the leaves of A. occidentale, E. globulus, P. guajava and fruits of X. aethiopica might be adopted for the management and/or amelioration of diabetes mellitus and its accompanying complications. Key words: Psidium guajava, Anacardium occidentale, Eucalyptus globules, Xylopia aethiopica, chloroform extracts.

In Vitro Activity of Xylopia Aethiopica Extracts Against Monacrosporium Bembicodes Isolated from Powdered Soyabean Samples

Abstract: Several incidences of antimycotic resistant have been reported and traced from the consumption of contaminated foods and their products. This study was carried out to determine the effects of Xylopia aethiopica on Monocrosporium bembicoides isolated from powdered Soyabean samples. A total of 120 powderd Soya bean sample were collected randomly from Uli community, Ihiala Local Government Area of Anambra State and screened for the presence of Monocrosporium bembicoides using spread plate technique. The isolates were subcultured and characterized using their macroscopic and microscopic characteristics. The seeds of Xylopia aethiopica was collected and screened for phytochemical constituents using spectrophotometer and gravimetric methods. The antifungal activity of the extract was carried out using agar well diffution technique. Tube dilution method was used to determine the minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC) of Xylopia aethiopica seed extract. A total of 24 powdered Soyabean samples out of 120 samples were positive to Monocrosporium bembicoides , of which the organism was seen most in samples collected from location C (Eke Agbagba market). The phytochemical analysis revealed the presence of alkaloids, flavonoids, phenolics, cardiac glycosides, tannins, steroids and saponins. The extracts showed pronounced activity against the tested Monocrosporium bembicoides of which ethanolic extract significantly (p< 0.05) inhibited the organisms more than the aqueous extracts. The ethanolic extract and ketoconazole had similar MIC and MFC. This study has shown the occurrence of Monocrosporium bembicoides in the studied powdered Soyabean samples, and Xylopia aethiopica seed extracts showed pronounced activity against the organism, of which ethanolic extract was more pronounced. Keywords: Monocrosporium bembicoides, Xylopia aethiopica, Soyabean,Phytochemical, Antifungal Activity