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Adi Stern
Researcher at Tel Aviv University
Publications - 60
Citations - 2924
Adi Stern is an academic researcher from Tel Aviv University. The author has contributed to research in topics: Mutation rate & Gene. The author has an hindex of 19, co-authored 52 publications receiving 2214 citations. Previous affiliations of Adi Stern include Weizmann Institute of Science & University of Massachusetts Amherst.
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Journal ArticleDOI
The phage-host arms race: Shaping the evolution of microbes
Adi Stern,Rotem Sorek +1 more
TL;DR: The unique and common features of phage resistance mechanisms and their role in global biodiversity are discussed and the commonalities between defense mechanisms suggest avenues for the discovery of novel forms of these mechanisms based on their evolutionary traits.
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Self-targeting by CRISPR: gene regulation or autoimmunity?
TL;DR: It is proposed that accidental incorporation of self nucleic acids by CRISPR can incur an autoimmune fitness cost, and this could explain the abundance of degradedCRISPR systems across prokaryotes.
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Selecton 2007: advanced models for detecting positive and purifying selection using a Bayesian inference approach
TL;DR: Selecton version 2.2 is an effective, user-friendly and freely available web server which implements up-to-date methods for computing site-specific selection forces, and the visualization of these forces on the protein's sequence and structure.
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Evidence for increased breakthrough rates of SARS-CoV-2 variants of concern in BNT162b2-mRNA-vaccinated individuals.
Talia Kustin,Noam Harel,Uriah Finkel,Shay Perchik,Sheri Harari,Maayan Tahor,Itamar Caspi,Rachel Levy,Michael Leshchinsky,Shifra Ken Dror,Galit Bergerzon,Hala Gadban,Faten Gadban,Eti Eliassian,Orit Shimron,Loulou Saleh,Haim Ben-Zvi,Elena Keren Taraday,Doron Amichay,Doron Amichay,Anat Ben-Dor,Dana Sagas,Merav Strauss,Yonat Shemer Avni,Amit Huppert,Amit Huppert,Eldad Kepten,Ran D. Balicer,Doron Netzer,Shay Ben-Shachar,Shay Ben-Shachar,Adi Stern +31 more
TL;DR: In this paper, a matched cohort study was conducted to examine the distribution of VOCs in infections of BNT162b2 mRNA vaccinees from Clalit Health Services (Israel) using viral genomic sequencing, and hypothesized that if vaccine effectiveness against a VOC is reduced, its proportion among breakthrough cases would be higher than in unvaccinated controls.
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CRISPR targeting reveals a reservoir of common phages associated with the human gut microbiome
TL;DR: The results imply that phage-bacterial attack-resistance interactions occur within the human gut microbiome, possibly affecting microbiota composition and human health.