Junjie Zai

TL;DR: Comprehensive sequence analysis and comparison in conjunction with relative synonymous codon usage (RSCU) bias among different animal species based on the 2019-nCoV sequence suggest that homologous recombination may occur and contribute to the 2019‐n coV cross‐species transmission.

TL;DR: The human SARS‐CoV‐2 virus, which is responsible for the recent outbreak of COVID‐19, did not come directly from pangolins, and a unique peptide (PRRA) insertion was identified in the human Sars‐CoVs2 virus that may be involved in the proteolytic cleavage of the spike protein by cellular proteases, and thus could impact host range and transmissibility.

TL;DR: To investigate the time origin, genetic diversity, and transmission dynamics of the recent 2019‐nCoV outbreak in China and beyond, a total of 32 genomes of virus strains sampled from China, Thailand, and the USA were analyzed.

TL;DR: The star‐like signal and topology of 2019‐nCoV may be indicative of potentially large “first generation” human‐to‐human virus transmission and that Wuhan is the major hub for the spread of the 2019‐ nCoV outbreak in China and elsewhere.

TL;DR: The results emphasize the importance of using phylodynamic analyses to provide insights into the roles of various interventions to limit the spread of SARS-CoV-2 in China and beyond.