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Ben Hu
Researcher at Chinese Academy of Sciences
Publications - 39
Citations - 26290
Ben Hu is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Coronavirus & Medicine. The author has an hindex of 19, co-authored 31 publications receiving 17774 citations.
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Journal ArticleDOI
A pneumonia outbreak associated with a new coronavirus of probable bat origin
Peng Zhou,Xing-Lou Yang,Xian Guang Wang,Ben Hu,Lei Zhang,Wei Zhang,Hao Rui Si,Yan Zhu,Bei Li,Chao Lin Huang,Hui-Dong Chen,Jing Chen,Yun Luo,Hua Guo,Ren Di Jiang,Meiqin Liu,Ying Chen,Xu Rui Shen,Xi Wang,Xiao Shuang Zheng,Kai Zhao,Quanjiao Chen,Fei Deng,Lin Lin Liu,Bing Yan,Fa Xian Zhan,Yan-Yi Wang,Gengfu Xiao,Zhengli Shi +28 more
TL;DR: Identification and characterization of a new coronavirus (2019-nCoV), which caused an epidemic of acute respiratory syndrome in humans in Wuhan, China, and it is shown that this virus belongs to the species of SARSr-CoV, indicates that the virus is related to a bat coronav virus.
Journal ArticleDOI
Characteristics of SARS-CoV-2 and COVID-19
TL;DR: The basic virology of SARS-CoV-2 is described, including genomic characteristics and receptor use, highlighting its key difference from previously known coronaviruses.
Journal ArticleDOI
Molecular and serological investigation of 2019-nCoV infected patients: implication of multiple shedding routes.
Wei Zhang,Rong-Hui Du,Bei Li,Xiao-Shuang Zheng,Xing-Lou Yang,Ben Hu,Yan-Yi Wang,Gengfu Xiao,Bing Yan,Zhengli Shi,Peng Zhou +10 more
TL;DR: Investigation on patients in a local hospital who were infected with a novel coronavirus found the presence of 2019-nCoV in anal swabs and blood, and more anal swab positives than oral swabs positives in a later stage of infection, suggesting shedding and thereby transmitted through oral–fecal route.
Journal ArticleDOI
Isolation and characterization of a bat SARS-like coronavirus that uses the ACE2 receptor
Xing-Yi Ge,Jia Lu Li,Xing-Lou Yang,Aleksei A. Chmura,Guangjian Zhu,Jonathan H. Epstein,Jonna A. K. Mazet,Ben Hu,Wei Zhang,Cheng Peng,Yu Ji Zhang,Chu Ming Luo,Bing Tan,Ning Wang,Yan Zhu,Gary Crameri,Shuyi Zhang,Lin-Fa Wang,Lin-Fa Wang,Peter Daszak,Zhengli Shi +20 more
TL;DR: These results provide the strongest evidence to date that Chinese horseshoe bats are natural reservoirs of SARS-CoV, and that intermediate hosts may not be necessary for direct human infection by some bat SL-CoVs, and highlight the importance of pathogen-discovery programs targeting high-risk wildlife groups in emerging disease hotspots.
Journal ArticleDOI
Discovery of a rich gene pool of bat SARS-related coronaviruses provides new insights into the origin of SARS coronavirus
Ben Hu,Leiping Zeng,Xing-Lou Yang,Xing-Yi Ge,Wei Zhang,Bei Li,Jia Zheng Xie,Xu Rui Shen,Yun Zhi Zhang,Ning Wang,Dong Sheng Luo,Xiao Shuang Zheng,Mei Niang Wang,Peter Daszak,Lin-Fa Wang,Jie Cui,Zhengli Shi +16 more
TL;DR: It is hypothesized that the direct progenitor of SARS-CoV may have originated after sequential recombination events between the precursors of these SARSr-CoVs, and highlights the necessity of preparedness for future emergence of Sars-like diseases.