Institution
Wuhan Jinyintan Hospital
Healthcare•Wuhan, China•
About: Wuhan Jinyintan Hospital is a healthcare organization based out in Wuhan, China. It is known for research contribution in the topics: Retrospective cohort study & Cohort study. The organization has 111 authors who have published 52 publications receiving 85960 citations. The organization is also known as: Jinyintan Hospital.
Topics: Retrospective cohort study, Cohort study, Odds ratio, ARDS, Coronavirus
Papers
More filters
TL;DR: The epidemiological, clinical, laboratory, and radiological characteristics and treatment and clinical outcomes of patients with laboratory-confirmed 2019-nCoV infection in Wuhan, China, were reported.
36,578 citations
TL;DR: Wang et al. as discussed by the authors used univariable and multivariable logistic regression methods to explore the risk factors associated with in-hospital death, including older age, high SOFA score and d-dimer greater than 1 μg/mL.
20,189 citations
TL;DR: Identification and characterization of a new coronavirus (2019-nCoV), which caused an epidemic of acute respiratory syndrome in humans in Wuhan, China, and it is shown that this virus belongs to the species of SARSr-CoV, indicates that the virus is related to a bat coronav virus.
Abstract: Since the outbreak of severe acute respiratory syndrome (SARS) 18 years ago, a large number of SARS-related coronaviruses (SARSr-CoVs) have been discovered in their natural reservoir host, bats1–4. Previous studies have shown that some bat SARSr-CoVs have the potential to infect humans5–7. Here we report the identification and characterization of a new coronavirus (2019-nCoV), which caused an epidemic of acute respiratory syndrome in humans in Wuhan, China. The epidemic, which started on 12 December 2019, had caused 2,794 laboratory-confirmed infections including 80 deaths by 26 January 2020. Full-length genome sequences were obtained from five patients at an early stage of the outbreak. The sequences are almost identical and share 79.6% sequence identity to SARS-CoV. Furthermore, we show that 2019-nCoV is 96% identical at the whole-genome level to a bat coronavirus. Pairwise protein sequence analysis of seven conserved non-structural proteins domains show that this virus belongs to the species of SARSr-CoV. In addition, 2019-nCoV virus isolated from the bronchoalveolar lavage fluid of a critically ill patient could be neutralized by sera from several patients. Notably, we confirmed that 2019-nCoV uses the same cell entry receptor—angiotensin converting enzyme II (ACE2)—as SARS-CoV. Characterization of full-length genome sequences from patients infected with a new coronavirus (2019-nCoV) shows that the sequences are nearly identical and indicates that the virus is related to a bat coronavirus.
16,857 citations
TL;DR: Characteristics of patients who died were in line with the MuLBSTA score, an early warning model for predicting mortality in viral pneumonia, and further investigation is needed to explore the applicability of the Mu LBSTA scores in predicting the risk of mortality in 2019-nCoV infection.
16,282 citations
TL;DR: The clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia who were admitted to the intensive care unit (ICU) of Wuhan Jin Yin-tan hospital between late December, 2019 and Jan 26, 2020 are described.
7,787 citations
Authors
Showing all 113 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| Li Zhang | 67 | 667 | 25692 |
| You Shang | 22 | 89 | 7772 |
| Ling Sang | 12 | 23 | 3830 |
| Yongran Wu | 9 | 21 | 6511 |
| Li Zhang | 9 | 14 | 43306 |
| Yuan Wei | 8 | 8 | 58280 |
| Shiying Yuan | 8 | 23 | 6391 |
| Dingyu Zhang | 7 | 9 | 7423 |
| Dingyu Zhang | 7 | 14 | 366 |
| Hong Liu | 6 | 14 | 6051 |
| Yanqing Fan | 6 | 9 | 2484 |
| Chaolin Huang | 5 | 8 | 143 |
| Ting Yu | 5 | 5 | 58163 |
| Ming Zhong | 5 | 6 | 174 |
| Lei Li | 5 | 6 | 417 |