Y
Yan-Yi Wang
Researcher at Chinese Academy of Sciences
Publications - 64
Citations - 24135
Yan-Yi Wang is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Innate immune system & IRF3. The author has an hindex of 28, co-authored 58 publications receiving 17671 citations. Previous affiliations of Yan-Yi Wang include Wuhan University.
Papers
More filters
Journal ArticleDOI
A pneumonia outbreak associated with a new coronavirus of probable bat origin
Peng Zhou,Xing-Lou Yang,Xian Guang Wang,Ben Hu,Lei Zhang,Wei Zhang,Hao Rui Si,Yan Zhu,Bei Li,Chao Lin Huang,Hui-Dong Chen,Jing Chen,Yun Luo,Hua Guo,Ren Di Jiang,Meiqin Liu,Ying Chen,Xu Rui Shen,Xi Wang,Xiao Shuang Zheng,Kai Zhao,Quanjiao Chen,Fei Deng,Lin Lin Liu,Bing Yan,Fa Xian Zhan,Yan-Yi Wang,Gengfu Xiao,Zhengli Shi +28 more
TL;DR: Identification and characterization of a new coronavirus (2019-nCoV), which caused an epidemic of acute respiratory syndrome in humans in Wuhan, China, and it is shown that this virus belongs to the species of SARSr-CoV, indicates that the virus is related to a bat coronav virus.
Journal ArticleDOI
Molecular and serological investigation of 2019-nCoV infected patients: implication of multiple shedding routes.
Wei Zhang,Rong-Hui Du,Bei Li,Xiao-Shuang Zheng,Xing-Lou Yang,Ben Hu,Yan-Yi Wang,Gengfu Xiao,Bing Yan,Zhengli Shi,Peng Zhou +10 more
TL;DR: Investigation on patients in a local hospital who were infected with a novel coronavirus found the presence of 2019-nCoV in anal swabs and blood, and more anal swab positives than oral swabs positives in a later stage of infection, suggesting shedding and thereby transmitted through oral–fecal route.
Journal ArticleDOI
The Adaptor Protein MITA Links Virus-Sensing Receptors to IRF3 Transcription Factor Activation
Bo Zhong,Yan Yang,Shu Li,Yan-Yi Wang,Ying Li,Feici Diao,Cao-Qi Lei,Xiao He,Lu Zhang,Po Tien,Hong-Bing Shu +10 more
TL;DR: The results suggest that MITA is a critical mediator of virus-triggered IRF3 activation and IFN expression and further demonstrate the importance of certain mitochondrial proteins in innate antiviral immunity.
Posted ContentDOI
Discovery of a novel coronavirus associated with the recent pneumonia outbreak in humans and its potential bat origin
Peng Zhou,Xing-Lou Yang,Xian Guang Wang,Ben Hu,Lei Zhang,Wei Zhang,Hao Rui Si,Yan Zhu,Bei Li,Chao Lin Huang,Hui-Dong Chen,Jing Chen,Yun Luo,Hua Guo,Ren Di Jiang,Meiqin Liu,Ying Chen,Xu Rui Shen,Xi Wang,Xiao Shuang Zheng,Kai Zhao,Quanjiao Chen,Fei Deng,Lin Lin Liu,Bing Yan,Fa Xian Zhan,Yan-Yi Wang,Gengfu Xiao,Zhengli Shi +28 more
TL;DR: The identification and characterization of a novel coronavirus (nCoV-2019) which caused an epidemic of acute respiratory syndrome in humans, in Wuhan, China, and it is confirmed that this novel CoV uses the same cell entry receptor, ACE2, as SARS-CoV.
Journal ArticleDOI
Addendum: A pneumonia outbreak associated with a new coronavirus of probable bat origin.
Peng Zhou,Xing-Lou Yang,Xian Guang Wang,Ben Hu,Lei Zhang,Wei Zhang,Hao Rui Si,Yan Zhu,Bei Li,Chao Lin Huang,Hui Dong Chen,Jing Chen,Yun Luo,Hua Guo,Ren Di Jiang,Mei Qin Liu,Ying Chen,Xu Rui Shen,Xi Wang,Xiao Shuang Zheng,Kai Zhao,Quanjiao Chen,Fei Deng,Lin Lin Liu,Bing Yan,Fa Xian Zhan,Yan-Yi Wang,Gengfu Xiao,Zhengli Shi +28 more