G
Gage K. Moreno
Researcher at University of Wisconsin-Madison
Publications - 29
Citations - 493
Gage K. Moreno is an academic researcher from University of Wisconsin-Madison. The author has contributed to research in topics: Medicine & MHC class I. The author has an hindex of 7, co-authored 22 publications receiving 142 citations.
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Journal ArticleDOI
Multiplexed CRISPR-based microfluidic platform for clinical testing of respiratory viruses and identification of SARS-CoV-2 variants
Nicole L. Welch,M. Zhu,Catherine Hua,Juliane Weller,Marzieh Ezzaty Mirhashemi,Tien G. Nguyen,Sreekar Mantena,Matthew R. Bauer,Bennett M. Shaw,Cheri M. Ackerman,Sri Gowtham Thakku,Megan Tse,Jared Kehe,Marie-Martine Uwera,Jacqueline S. Eversley,D.A. Bielwaski,Graham McGrath,Joseph Braidt,Jeremy Johnson,Felecia Cerrato,Gage K. Moreno,Lydia A. Krasilnikova,Brittany A. Petros,Gabrielle Gionet,Ewa King,Richard C. Huard,S. Jalbert,Michael L. Cleary,N. Fitzgerald,Stacey Gabriel,Glen R. Gallagher,Sandra Smole,Lawrence C. Madoff,Catherine M. Brown,Matthew W. Keller,Malania M. Wilson,M. Kirby,John R. Barnes,Daniel J. Park,Katherine J. Siddle,Christian T. Happi,Deborah T. Hung,Michael Springer,Bronwyn MacInnis,Jacob E. Lemieux,Eric S. Rosenberg,John A. Branda,Paul C. Blainey,Pardis C. Sabeti,Cameron Myhrvold +49 more
TL;DR: In this article , a cost-effective virus and variant detection platform, called microfluidic Combinatorial Arrayed Reactions for Multiplexed Evaluation of Nucleic acids (mCARMEN), is presented.
Journal ArticleDOI
Transmission of SARS-CoV-2 in domestic cats imposes a narrow bottleneck.
Katarina M. Braun,Gage K. Moreno,Peter Halfmann,Emma B. Hodcroft,David A. Baker,Emma C. Boehm,Andrea M. Weiler,Amelia K. Haj,Masato Hatta,Shiho Chiba,Tadashi Maemura,Yoshihiro Kawaoka,Katia Koelle,David H. O’Connor,Thomas C. Friedrich +14 more
TL;DR: In this paper, the authors used domestic cats as a model to study the evolutionary mechanisms by which SARS-CoV-2 viruses adapt to mammalian hosts and undergo antigenic evolution depend on the ways genetic variation is generated and selected within and between individual hosts.
Journal ArticleDOI
Acute SARS-CoV-2 infections harbor limited within-host diversity and transmit via tight transmission bottlenecks.
Katarina M. Braun,Gage K. Moreno,Cassia Wagner,Molly A. Accola,William M. Rehrauer,David A. Baker,Katia Koelle,David H. O’Connor,Trevor Bedford,Thomas C. Friedrich,Louise H. Moncla +10 more
TL;DR: The authors found that within-host diversity is low and transmission bottlenecks are narrow, with very few viruses founding most infections, and most variation generated within host is lost during transmission.
Journal ArticleDOI
Revealing fine-scale spatiotemporal differences in SARS-CoV-2 introduction and spread.
Gage K. Moreno,Katarina M. Braun,Kasen K. Riemersma,Michael A. Martin,Peter Halfmann,Chelsea M. Crooks,Trent M. Prall,David Baker,John J. Baczenas,Anna S. Heffron,Mitchell D. Ramuta,Manjeet Khubbar,Andrea M. Weiler,Molly A. Accola,William M. Rehrauer,Shelby L. O’Connor,Nasia Safdar,Caitlin S. Pepperell,Trivikram Dasu,Sanjib Bhattacharyya,Yoshihiro Kawaoka,Katia Koelle,David H. O’Connor,Thomas C. Friedrich +23 more
TL;DR: Analysis of 247 full-genome SARS-CoV-2 sequences from two nearby communities in Wisconsin, USA finds surprisingly distinct patterns of viral spread, which suggest patterns of Sars-Cov-2 transmission may vary substantially even in nearby communities.
Journal ArticleDOI
Viral Sequencing to Investigate Sources of SARS-CoV-2 Infection in US Healthcare Personnel.
Katarina M. Braun,Gage K. Moreno,Ashley Buys,Elizabeth D Somsen,Max Bobholz,Molly A. Accola,Laura Anderson,William M. Rehrauer,David A. Baker,Nasia Safdar,Alexander J. Lepak,David H. O’Connor,Thomas C. Friedrich +12 more
TL;DR: In this paper, the authors investigated the likely source of SARS-CoV-2 infection in healthcare personnel (HCP) at a major academic medical institution in the Upper Midwest of the United States between 25 March - 27 December, 2020.