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Angela Flannery
Researcher at AstraZeneca
Publications - 2
Citations - 720
Angela Flannery is an academic researcher from AstraZeneca. The author has contributed to research in topics: Lung cancer & Epidermal growth factor receptor. The author has an hindex of 1, co-authored 2 publications receiving 707 citations.
Papers
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Journal ArticleDOI
Molecular predictors of outcome with gefitinib in a phase III placebo-controlled study in advanced non-small-cell lung cancer
Fred R. Hirsch,M. Varella-Garcia,Paul A. Bunn,Wilbur A. Franklin,Rafal Dziadziuszko,Nick Thatcher,Alex Chang,Purvish M. Parikh,J. R. Pereira,Tudor Ciuleanu,Joachim von Pawel,Claire Watkins,Angela Flannery,Gillian Ellison,Emma Donald,Lucy Knight,D V Parums,Nicholas Botwood,Brian Holloway +18 more
TL;DR: EGFR gene copy number was a predictor of clinical benefit from gefitinib in ISEL, and the limited amount of data collected for KRAS and BRAF mutations prevented any meaningful evaluation of clinical outcomes in relation to these mutations.
Patent
Diagnostic methods based on polymorphisms of glucosyltransferase-like protein
TL;DR: In this paper, an association between the gene encoding glucosyltransferase-like protein (GT) and osteoarthritis (OA) was identified, and diagnostic techniques for determining a patient's susceptibility to develop OA by detecting all or part of the GT gene, its precursors or products (mRNA, cDNA, genomic DNA, or protein).