A
Anna Z. Amar
Researcher at National Institutes of Health
Publications - 2
Citations - 1057
Anna Z. Amar is an academic researcher from National Institutes of Health. The author has contributed to research in topics: IL-2 receptor & Interleukin 21. The author has an hindex of 2, co-authored 2 publications receiving 1049 citations.
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Journal Article
CD4+CD25+ T Cells Inhibit Both the Induction and Effector Function of Autoreactive T Cells and Represent a Unique Lineage of Immunoregulatory Cells
TL;DR: The population of CD4+CD25+ immunoregulatory cells is characterized and it is demonstrated that they can suppress not only the induction of disease post-thymectomy, but can also efficiently suppress disease induced by cloned autoantigen-specific effector cells.
Journal ArticleDOI
Post-thymectomy autoimmune gastritis: fine specificity and pathogenicity of anti-H/K ATPase-reactive T cells.
Elisabeth Suri-Payer,Anna Z. Amar,Rebecca S. McHugh,Kannan Natarajan,David H. Margulies,Ethan M. Shevach +5 more
TL;DR: It is demonstrated that freshly explanted gastric lymph node (LN) cells from d3Tx mice react significantly to the H/K ATPase α chain, but only marginally to the β chain, which strongly suggests that this suppressor T cell population may have a therapeutic role in other models of established autoimmunity.