D
David Stopak
Researcher at University of North Carolina at Chapel Hill
Publications - 4
Citations - 2993
David Stopak is an academic researcher from University of North Carolina at Chapel Hill. The author has contributed to research in topics: Silicone rubber & Traction (orthopedics). The author has an hindex of 4, co-authored 4 publications receiving 2882 citations.
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Journal ArticleDOI
Silicone rubber substrata: a new wrinkle in the study of cell locomotion
TL;DR: When tissue cells are cultured on very thin sheets of cross-linked silicone fluid, the traction forces the cells exert are made visible as elastic distortion and wrinkling of this substratum.
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Fibroblast traction as a mechanism for collagen morphogenesis
TL;DR: It is proposed that this morphogenetic rearrangement of extracellular matrices is the primary function of fibroblast traction and explains its excessive strength.
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Connective tissue morphogenesis by fibroblast traction: I. Tissue culture observations
David Stopak,Albert K. Harris +1 more
TL;DR: It is found that the force fibroblasts use to propel themselves (traction) is sufficiently strong to distort collagen gels and to form patterns of tension, compression, and alignment similar to the wrinkling patterns previously observed on silicone rubber.
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Generation of spatially periodic patterns by a mechanical instability: a mechanical alternative to the Turing model.
TL;DR: It is proposed that an equivalent mechanical instability, occurring during the embryonic development of this skin, could be the cause not only of the clumping of dermal fibroblasts to form the feather papillae, but also of the alignment of collagen fibres into the characteristic polygonal network of fibre bundles - which interconnect these Papillae and which presage the subsequent pattern of the dermal muscles serving to control feather movements.