D
Dirk R. Larson
Researcher at Mayo Clinic
Publications - 295
Citations - 27404
Dirk R. Larson is an academic researcher from Mayo Clinic. The author has contributed to research in topics: Monoclonal gammopathy of undetermined significance & Population. The author has an hindex of 79, co-authored 271 publications receiving 24067 citations. Previous affiliations of Dirk R. Larson include University of California, San Francisco & Dartmouth–Hitchcock Medical Center.
Papers
More filters
Journal ArticleDOI
Review of 1027 Patients With Newly Diagnosed Multiple Myeloma
Robert A. Kyle,Morie A. Gertz,Thomas E. Witzig,John A. Lust,Martha Q. Lacy,Angela Dispenzieri,Rafael Fonseca,S. Vincent Rajkumar,Janice R. Offord,Dirk R. Larson,Matthew E. Plevak,Terry M. Therneau,Philip R. Greipp +12 more
TL;DR: Multivariate analysis revealed that age, plasma cell labeling index, low platelet count, serum albumin value, and the log of the creatinine value were the most important prognostic factors for newly diagnosed multiple myeloma.
Journal ArticleDOI
A long-term study of prognosis in monoclonal gammopathy of undetermined significance.
Robert A. Kyle,Terry M. Therneau,S. Vincent Rajkumar,Janice R. Offord,Dirk R. Larson,Matthew F. Plevak,L. Joseph Melton +6 more
TL;DR: The risk of progression of MGUS to multiple myeloma or related disorders is about 1 percent per year, and the initial concentration of serum monoclonal protein was a significant predictor of progression at 20 years.
Journal ArticleDOI
Prevalence of Total Hip and Knee Replacement in the United States.
Hilal Maradit Kremers,Dirk R. Larson,Cynthia S. Crowson,Walter K. Kremers,Raynard Washington,Claudia A. Steiner,William A. Jiranek,Daniel J. Berry +7 more
TL;DR: Around 7 million Americans are living with a hip or knee replacement, and consequently, in most cases, are mobile, despite advanced arthritis, and these numbers underscore the substantial public health impact of total hip and knee arthroplasties.
Journal ArticleDOI
Prevalence of Monoclonal Gammopathy of Undetermined Significance
Robert A. Kyle,Terry M. Therneau,S. Vincent Rajkumar,Dirk R. Larson,Matthew F. Plevak,Janice R. Offord,Angela Dispenzieri,Jerry A. Katzmann,L. Joseph Melton +8 more
TL;DR: Among residents of Olmsted County, Minnesota, MGUS was found in 3.2% of persons 50 years of age or older and 5.3 percent of persons 70 years ofAge or older, which are higher in men than in women.
Journal ArticleDOI
Clinical course and prognosis of smoldering (asymptomatic) multiple myeloma.
Robert A. Kyle,Ellen D. Remstein,Terry M. Therneau,Angela Dispenzieri,Paul J. Kurtin,Janice M. Hodnefield,Dirk R. Larson,Matthew F. Plevak,Diane F. Jelinek,Rafael Fonseca,Lee Joseph Melton,S. Vincent Rajkumar +11 more
TL;DR: The risk of progression from smoldering multiple myeloma to symptomatic disease is related to the proportion of bone marrow plasma cells and the serum monoclonal protein level at diagnosis.