http://academic.oup.com/milmed/article-pdf/145/12/852/24134232/milmed-145-12-852.pdf

Zoonoses and Communicable Diseases Common to Man and Animals

Brucellosis is a zoonotic disease of great animal welfare and economic implications worldwide known since ancient times. The emergence of brucellosis in new areas as well as transmission of brucellosis from wild and domestic animals is of great significance in terms of new epidemiological dimensions. Brucellosis poses a major public health threat by the consumption of non-pasteurized milk and milk products produced by unhygienic dairy farms in endemic areas. Regular and meticulous surveillance is essentially required to determine the true picture of brucellosis especially in areas with continuous high prevalence. Additionally, international migration of humans, animals and trade of animal products has created a challenge for disease spread and diagnosis in non-endemic areas. Isolation and identification remain the gold standard test, which requires expertise. The advancement in diagnostic strategies coupled with screening of newly introduced animals is warranted to control the disease. Of note, the diagnostic value of miRNAs for appropriate detection of B. abortus infection has been shown. The most widely used vaccine strains to protect against Brucella infection and related abortions in cattle are strain 19 and RB51. Moreover, it is very important to note that no vaccine, which is highly protective, safe and effective is available either for bovines or human beings. Research results encourage the use of bacteriophage lysates in treatment of bovine brucellosis. One Health approach can aid in control of this disease, both in animals and man.

Bovine brucellosis - a comprehensive review.

Objectives Human brucellosis is a public health problem endangering health and property in China. Predicting the trend and the seasonality of human brucellosis is of great significance for its prevention. In this study, a comparison between the autoregressive integrated moving average (ARIMA) model and the eXtreme Gradient Boosting (XGBoost) model was conducted to determine which was more suitable for predicting the occurrence of brucellosis in mainland China. Design Time-series study. Setting Mainland China. Methods Data on human brucellosis in mainland China were provided by the National Health and Family Planning Commission of China. The data were divided into a training set and a test set. The training set was composed of the monthly incidence of human brucellosis in mainland China from January 2008 to June 2018, and the test set was composed of the monthly incidence from July 2018 to June 2019. The mean absolute error (MAE), root mean square error (RMSE) and mean absolute percentage error (MAPE) were used to evaluate the effects of model fitting and prediction. Results The number of human brucellosis patients in mainland China increased from 30 002 in 2008 to 40 328 in 2018. There was an increasing trend and obvious seasonal distribution in the original time series. For the training set, the MAE, RSME and MAPE of the ARIMA(0,1,1)×(0,1,1)12 model were 338.867, 450.223 and 10.323, respectively, and the MAE, RSME and MAPE of the XGBoost model were 189.332, 262.458 and 4.475, respectively. For the test set, the MAE, RSME and MAPE of the ARIMA(0,1,1)×(0,1,1)12 model were 529.406, 586.059 and 17.676, respectively, and the MAE, RSME and MAPE of the XGBoost model were 249.307, 280.645 and 7.643, respectively. Conclusions The performance of the XGBoost model was better than that of the ARIMA model. The XGBoost model is more suitable for prediction cases of human brucellosis in mainland China.

https://bmjopen.bmj.com/content/bmjopen/10/12/e039676.full.pdf

Comparison of ARIMA model and XGBoost model for prediction of human brucellosis in mainland China: a time-series study.

Prevalence of Haemophilus parasuis"Glaesserella parasuis" in pigs in China: A systematic review and meta-analysis.

Seroprevalence of Toxoplasma gondii in cattle in China from 2010 to 2019: A systematic review and meta-analysis.

Brucellosis seroprevalence in dairy cattle in China during 2008-2018: A systematic review and meta-analysis.

Brucellosis remains one of the most common zoonotic diseases globally, with more than half million human cases reported annually. Brucellosis is an emerging and re-emerging disease in China since the 1990s. An infectious reservoir constituted by domestic animals with brucellosis, especially ovine and caprine herds, poses a significant threat to public health. The seroprevalence of brucellosis in sheep and goat flocks in a national context is unavailable so far. Therefore, we conducted this systematic review and meta-analysis to assess the overall status of brucellosis in sheep and goats in China in almost two decades. The pooled prevalence of brucellosis in ovine and caprine flocks in China increased in 2000–2009 (1.00%; 95% CI, 0.70–1.30) to 2010–2018 (3.20%; 95% CI, 2.70–3.60). The seroprevalence of brucellosis in sheep and goat flocks was higher in Eastern China, with 7.00% of positive rate, than that in any other region, especially Shandong province (18.70%). Brucellosis is highly endemic in some local regions. The high prevalence of brucellosis in agricultural regions is suggestive of a shift of geographic distribution. The pooled prevalence of brucellosis is higher in goat flocks than in sheep flocks in China. The overall data in this meta-analysis demands comprehensive intervention measures and further surveillance to facilitate the control of brucellosis in livestock. Further studies aimed at evaluating the risk factors associated with spreads of brucellosis in domestic animals unaddressed so far, and sufficient epidemiological data is important to the exploration and understanding of the prevalent status of brucellosis throughout the country and to disease control.

/pdf/brucellosis-seroprevalence-in-ovine-and-caprine-flocks-in-28rtcclxk1.pdf

Brucellosis seroprevalence in ovine and caprine flocks in China during 2000–2018: a systematic review and meta-analysis

For children aged 7–8 years in China, “immobility” is a key problem hindering their physical and mental development in recent years. It is widely accepted that motor performance development in children is accompanied by physical and mental growth and development. However, few studies have clarified the relationship among motor behavior, motor development and motor performance. To bridge this knowledge gap, an empirical analysis of children aged 7–8 years in China was conducted. This study developed scales for testing motor performance, motor behavior and motor performance, respectively, and collected data of these tests on children aged 7–8 years in China. Canonical correlation analysis was used to analyze the correlations among motor performance, motor behavior and motor performance, and partial least squares regression was used to evaluate the relationship between dependent and independent variables. It was found that, for the children aged 7–8 years in China, there were significant positive correlations among the motor performance, motor behavior, and motor development. The three tests were closely related and could be applied to promote children's sports performance through improved training activities for targeting specific indicators. The study found there was no significant differences in the application of the three tests for children with different age and gender. This finding lays a foundation for further testing in older children and meets the measurement requirements of modern medicine's “bio-psycho-social model of health promotion”. Additionally, the theoretical motional quotient model of “The Bio-Behavior-Task” is constructed as a comprehensive motor performance evaluation system, aligning with students' physical and mental development standards.

/pdf/relationship-among-motor-behavior-motor-development-and-1v94aho4.pdf

Relationship Among Motor Behavior, Motor Development, and Motor Performance in Children Aged 7–8 Years in China

The original article [1] contained a minor error whereby Table 1 was typeset incorrectly.

/pdf/correction-to-brucellosis-seroprevalence-in-ovine-and-1tprmp6wma.pdf

Jiajia Cheng

Papers

Brucellosis seroprevalence in dairy cattle in China during 2008-2018: A systematic review and meta-analysis.

Brucellosis seroprevalence in ovine and caprine flocks in China during 2000–2018: a systematic review and meta-analysis

Relationship Among Motor Behavior, Motor Development, and Motor Performance in Children Aged 7–8 Years in China

Correction to: Brucellosis seroprevalence in ovine and caprine flocks in China during 2000-2018: a systematic review and meta-analysis.