Antimicrobial and antiviral nanocomposites based on polylactic acid (PLA) and chitosan were synthesized by a thermochemical reduction method of Ag+ ions in the PLA-Ag+-chitosan polymer films. Features of the structural, morphological, thermophysical, antimicrobial, antiviral, and cytotoxic properties of PLA-Ag-chitosan nanocomposites were studied by X-ray diffraction (XRD), transmission electron microscopy (TEM), differential scanning calorimetry (DSC), thermogravimetric analysis (TGA), and antiviral, antimicrobial, and cytotoxic studies. The effects of temperature and the duration of reduction of Ag+ ions on the structure of PLA-Ag-chitosan nanocomposites were established. During the thermochemical reduction (T = 160 °C, t = 5 min) of silver palmitate ions in PLA-Ag+-chitosan polymer films, Ag nanoparticles with an average size of 4.2 nm were formed. PLA-Ag-chitosan polymer nanocomposites have strong antimicrobial activity against S. aureus and E. coli strains. In particular, for PLA-chitosan samples containing 4% Ag, the diameters of the S. aureus and E. coli growth inhibition zones were 25.8 and 25.0 mm, respectively. The antiviral activity of the nanocomposites against influenza A virus, herpes simplex virus type 1, and adenovirus serotype 2 was also revealed. The PLA-4%Ag-chitosan nanocomposites completely inhibited the cytopathic effect (CPE) of herpes virus type 1 by 5.12 log10TCID50/mL (high antiviral activity) and the development of the CPE of influenza virus and adenovirus by 0.60 and 1.07 log10TCID50/mL (relative antiviral activity). The obtained nanocomposites were not cytotoxic; they did not inhibit the viability of MDCK, BHK-21, and Hep-2 cell cultures.

Preparation, Characterization, and Antimicrobial and Antiviral Properties of Silver-Containing Nanocomposites Based on Polylactic Acid-Chitosan.

https://doi.org/10.1016/j.cobme.2022.100395

Antimicrobial polymeric composites for high-touch surfaces in healthcare applications

Naked-eye sensing and target-guiding treatment of bacterial infection using pH-tunable multicolor luminescent lanthanide-based hydrogel.

Naked-eye sensing and target-guiding treatment of bacterial infection using pH-tunable multicolor luminescent lanthanide-based hydrogel

Chitosan is a biopolymer obtained from deacetylation of the abundant natural chitin polymer. It has found its use in many applications due to its unique solubility as well as chemical and biological properties. In addition to its biodegradability and biocompatibility, it has many reactive amino side groups that offer the possibilities of chemical modification and formation of a large variety of beneficial derivatives. Numerous researchers have published works outlining the physical and chemical properties of chitosan, as well as its use in several industries, such as medical, environmental and food. Due to its excellent absorption and biological properties, chitosan present a myriad of opportunities in eco-friendly textile processes. Chitosan is able to confer antimicrobial, antiviral, anti-odor and other biological activities to textile fibers and fabrics. In this review, the first part is dedicated to developing the physio-chemical and biological characteristics of chitosan. Then, we present chitosan applications in the textile industry over the past decade. Literature works on chitosan usage along with different textile production steps (fiber formation, functional treatments, dyeing and effluent treatment) are extensively discussed.

Chitosan: A biopolymer for textile processes and products

In recent years, the textile industry has been seeking to develop innovative products. It is a good choice to organically combine materials with superior functional characteristics and commercial t...

Jianhui Li

Papers

Chitosan Natural Polymer Material for Improving Antibacterial Properties of Textiles