M
Michelle Iacobucci
Researcher at University Health Network
Publications - 25
Citations - 3676
Michelle Iacobucci is an academic researcher from University Health Network. The author has contributed to research in topics: Major depressive disorder & Cognition. The author has an hindex of 10, co-authored 22 publications receiving 1396 citations.
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Journal ArticleDOI
Impact of COVID-19 pandemic on mental health in the general population: A systematic review.
Jiaqi Xiong,Orly Lipsitz,Flora Nasri,Leanna M.W. Lui,Hartej Gill,Lee Phan,David Chen-Li,Michelle Iacobucci,Roger C.M. Ho,Amna Majeed,Roger S. McIntyre +10 more
TL;DR: The COVID-19 pandemic is associated with highly significant levels of psychological distress that, in many cases, would meet the threshold for clinical relevance.
Journal ArticleDOI
Recognition and Treatment of Cognitive Dysfunction in Major Depressive Disorder.
Hannah Zuckerman,Zihang Pan,Zihang Pan,Caroline Park,Caroline Park,Elisa Brietzke,Elisa Brietzke,Natalie Musial,Aisha S. Shariq,Michelle Iacobucci,Samantha J. Yim,Leanna M.W. Lui,Carola Rong,Roger S. McIntyre +13 more
TL;DR: The current narrative review aims to delineate the importance and relevance of cognitive dysfunction as a symptomatic target for prevention and treatment in the phenomenology of MDD.
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The effect of intravenous, intranasal, and oral ketamine in mood disorders: A meta-analysis.
Roger S. McIntyre,Isabelle P. Carvalho,Leanna M.W. Lui,Amna Majeed,Prakash S. Masand,Hartej Gill,Nelson B. Rodrigues,Orly Lipsitz,Alexandria C. Coles,Yena Lee,Jocelyn K. Tamura,Michelle Iacobucci,Lee Phan,Flora Nasri,Nikhita Singhal,Elizabeth Wong,Mehala Subramaniapillai,Rodrigo B. Mansur,Roger C.M. Ho,Raymond W. Lam,Joshua D. Rosenblat +20 more
TL;DR: The short-term efficacy of intravenous and intranasal ketamine/esketamine for adults with TRD was established and the efficacy of oral ketamine was limited by the need for studies with larger samples across independent sites.
Journal ArticleDOI
The neural systems of emotion regulation and abnormalities in major depressive disorder
Caroline Park,Caroline Park,Joshua D. Rosenblat,Yena Lee,Zihang Pan,Bing Cao,Michelle Iacobucci,Roger S. McIntyre +7 more
TL;DR: The main objectives of the current narrative review are to summarize the major neural systems involved in emotion regulation in humans, and to describe how these systems are dysregulated in MDD.
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The Efficacy of Vortioxetine on Anhedonia in Patients With Major Depressive Disorder
Bing Cao,Caroline Park,Mehala Subramaniapillai,Yena Lee,Yena Lee,Michelle Iacobucci,Rodrigo B. Mansur,Hannah Zuckerman,Lee Phan,Roger S. McIntyre +9 more
TL;DR: The unmet need in depression is to improve patient functioning and other patient-reported outcomes (e.g., quality of life), and antidepressant interventions capable of attenuating anhedonia as well as cognitive dysfunction in MDD may help in this regard.