N
Nina Schumacher
Researcher at University of Lübeck
Publications - 10
Citations - 189
Nina Schumacher is an academic researcher from University of Lübeck. The author has contributed to research in topics: Cyclosporin a & Ex vivo. The author has an hindex of 4, co-authored 10 publications receiving 175 citations.
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Treatment of severe pemphigus with a combination of immunoadsorption, rituximab, pulsed dexamethasone and azathioprine/mycophenolate mofetil: a pilot study of 23 patients
Michael Kasperkiewicz,Iakov Shimanovich,Markus Meier,Nina Schumacher,Lilia Westermann,J. Kramer,Detlef Zillikens,Enno Schmidt +7 more
TL;DR: This data indicates that a combination of immunoadsorption and rituximab with daily use of high‐dose oral corticosteroids and azathioprine/mycophenolate mofetil may induce a rapid and durable remission in severe, treatment‐resistant pemphigus.
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Delayed Cytokine mRNA Expression Kinetics after T-Lymphocyte Costimulation: A Quantitative Measure of the Efficacy of Cyclosporin A-based Immunosuppression
TL;DR: A delayed increase in cytokine mRNA expression during T-cell costimulation may represent a sensitive effect of immunosuppression and the parameter "area of cytokineRNA expression over time", which should include absolute cytokine RNA values at two different time points of mRNA kinetics is suggested.
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Sensitivity of whole-blood T lymphocytes in individual patients to tacrolimus (FK 506): impact of interleukin-2 mRNA expression as surrogate measure of immunosuppressive effect.
Christoph Härtel,Nina Schumacher,Lutz Fricke,Brigitte Ebel,Holger Kirchner,Michael Müller-Steinhardt +5 more
TL;DR: The results suggest an individual degree of calcineurin inhibitor sensitivity of activated whole-blood lymphocytes based on IL-2 mRNA expression is possible in patients undergoing tacrolimus or CsA monotherapy before living-donor kidney transplantation.
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Individual variability in cyclosporin A sensitivity: the assessment of functional measures on CD28-mediated costimulation of human whole blood T lymphocytes.
Christoph Härtel,Hans Jörg Hammers,Peter Schlenke,Lutz Fricke,Nina Schumacher,Holger Kirchner,Michael Müller-Steinhardt +6 more
TL;DR: This article found that cyclosporin A (CsA) effects might be helpful for optimizing immunosuppressive treatment after allogeneic organ transplantation in individual patients, as rejection can occur despite the existence of CsA blood levels within therapeutic ranges.
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Evaluation and Comparison of Clinical and iLaboratory Characteristics of Patients With IgA Epidermolysis Bullosa Acquisita, Linear IgA Bullous Dermatosis, and IgG Epidermolysis Bullosa Acquisita.
TL;DR: In this article, the authors defined the clinical features and treatment responses of Epidermolysis bullosa acquisita (EBA) and compared the prevalences of IgA EBA anti-BP180-driven LABD and classic IgG-mediated EBA in an autoimmune diagnostic laboratory database.