Complexes of heterocyclic thione donors

The Tautomerism of Heterocycles: Five-membered Rings with Two or More Heteroatoms

Gold nanoparticles (AuNPs) stabilized with mercaptothiadiazole ligands, 2,5-dimercapto-1,3,4-thiadiazole (DMT), 5-amino-2-mercapto-1,3,4-thiadiazole (AMT) and 5-methyl-2-mercapto-1,3,4-thiadiazole (MMT), were prepared by the reaction of the respective ligands with HAuCl4 and NaBH4 in an aqueous medium. TEM images show that the average size of AuNPs was 6.5 ± 0.5 nm, irrespective of the capping ligands. The colloidal solution of both DMT-capped AuNPs (DMT-AuNPs) and AMT-capped AuNPs (AMT-AuNPs) were highly stable for several months. However, several changes were noticed for MMT-capped AuNPs (MMT-AuNPs) after 2 h from its formation. The SPR band intensity at 518 nm decreases and the narrow SPR absorption band slowly changes into a flat absorption pattern with a broad peak from 518 to 1000 nm which was accompanied by a colour change of the solution from red to purple and then blue and thereafter unchanged. The TEM image of MMT-AuNPs after 96 h shows that most of the spherical shape of the AuNPs assembled to form a nanowire-like structure. The observed changes may be due to the absence of a strong stabilizing force on the surface of the MMT-AuNPs. The amino and thiolate groups on the surface of the AMT-AuNPs and DMT-AuNPs, respectively, were directly self-assembled on Au electrodes. They exhibit excellent electrocatalytic activity towards the oxidation of AA by enhancing its oxidation current twice in addition to more than 200 mV negative shift in the oxidation potential in contrast to bare Au electrode.

https://iopscience.iop.org/article/10.1088/0957-4484/19/8/085602/pdf

Synthesis of mercaptothiadiazole-functionalized gold nanoparticles and their self-assembly on Au substrates.

Protection of copper corrosion in 0.5 M NaCl solution by modification of 5-mercapto-3-phenyl-1,3,4-thiadiazole-2-thione potassium self-assembled monolayer

We report on the exploitation of metal-organic coordination polymers (MOCPs) as new and efficient matrixes to immobilize enzymes for amperometric biosensing of glucose or phenols. A ligand, 2,5-dimercapto-1,3,4-thiadiazole (DMcT), two metallic salts, NaAuCl(4) and Na(2)PtCl(6), and two enzymes, glucose oxidase (GOx) and tyrosinase, are used to demonstrate the novel concept. Briefly, one of the metallic salts is added into an aqueous suspension containing DMcT and one of the enzymes to trigger the metal-organic coordination reaction, and the yielded MOCPs-enzyme biocomposite (MEBC) is then cast-coated on an Au electrode for biosensing. The aqueous-phase coordination polymerization reactions of the metallic ions with DMcT are studied by visual inspection as well as some spectroscopic, microscopic, and electrochemical methods. The thus-prepared glucose and phenolic biosensors perform better in analytical performance (such as sensitivity and limit of detection) than those prepared by the conventional chemical and/or electrochemical polymerization methods and most of the reported analogous biosensors, as a result of the improved enzyme load/activity and mass-transfer efficiency after using the MOCPs materials with high adsorption/encapsulation capability and unique porous structure. For instance, the detection limit for catechol is as low as 0.2 nM here, being order(s) lower than those of most of the reported analogues. The enzyme electrode was also used to determine catachol in real samples with satisfactory results. The emerging MOCPs materials and the suggested aqueous-phase preparation strategy may find wide applications in the fields of bioanalysis, biocatalysis, and environmental monitoring.

S.A.A. Zaidi

Papers

Spectral and magnetic studies on the complexes of 2,5-dimercapto-1,3,4-thiadiazole (bismuthiol I) with Co(II), Ni(II), Zn(II), Cd(II) and Hg(II)

The nature of the complexes of 2,5-dimercapto 1,3,4-thiadiazole (bismuthiol)I)) with copper(I) and copper(II)

Ionization of ureas carbazides and carbazones in chlorosulphuric acid

Germanium(IV) chloride complexes with some nitrogen containing ligands

Complexes of 5-aminoindazole