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Shanique B. Alabi
Researcher at Yale University
Publications - 2
Citations - 314
Shanique B. Alabi is an academic researcher from Yale University. The author has contributed to research in topics: Proteolysis targeting chimera & Protein degradation. The author has an hindex of 2, co-authored 2 publications receiving 141 citations.
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Journal ArticleDOI
Androgen receptor degradation by the proteolysis-targeting chimera ARCC-4 outperforms enzalutamide in cellular models of prostate cancer drug resistance.
Jemilat Salami,Shanique B. Alabi,Ryan R. Willard,Nick J. Vitale,Jing Wang,Hanqing Dong,Meizhong Jin,Donald P. McDonnell,Andrew P. Crew,Taavi K. Neklesa,Craig M. Crews +10 more
TL;DR: A head-to-head comparison between a currently approved androgen receptor antagonist enzalutamide and its PROTAC derivative, ARCC-4, across different cellular models of prostate cancer drug resistance is performed.
Journal ArticleDOI
Major advances in targeted protein degradation: PROTACs, LYTACs, and MADTACs.
Shanique B. Alabi,Craig M. Crews +1 more
TL;DR: Targeted protein degradation (TPD) as discussed by the authors is a novel and innovative chemical tool and therapeutic modality that facilitates complete removal of the protein molecules from within or outside the cell.