S
Sofía Bernal-Silva
Researcher at Universidad Autónoma de San Luis Potosí
Publications - 20
Citations - 181
Sofía Bernal-Silva is an academic researcher from Universidad Autónoma de San Luis Potosí. The author has contributed to research in topics: Virus & Immune system. The author has an hindex of 5, co-authored 17 publications receiving 115 citations. Previous affiliations of Sofía Bernal-Silva include Oklahoma State University Center for Health Sciences.
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Expression and function of the purinergic receptor P2X7 in patients with pulmonary tuberculosis
S. Franco-Martínez,Perla Niño-Moreno,Sofía Bernal-Silva,Lourdes Baranda,M. Rocha-Meza,Liliana Portales-Cervantes,Esther Layseca-Espinosa,Roberto González-Amaro,Diana P. Portales-Pérez +8 more
TL;DR: Although the PBMC from TB patients do not show apparent abnormalities in the expression of P2X7, and the intracellular signals generated through it, the pattern of gene expression induced by ATP in these cells is different from that found in healthy contacts.
Journal ArticleDOI
Respiratory Syncytial Virus-A ON1 Genotype Emergence in Central Mexico in 2009 and Evidence of Multiple Duplication Events.
Andreu Comas-García,Daniel E. Noyola,Sandra Cadena-Mota,Montserrat Rico-Hernández,Sofía Bernal-Silva +4 more
TL;DR: ON1 strains include viruses that appear to be the result of at least 3 independent duplication events, and molecular data of strains from diverse geographical regions should help define the frequency and implications of this evolution mechanism.
Journal ArticleDOI
Intensive Care Unit Admission and Death Rates of Infants Admitted With Respiratory Syncytial Virus Lower Respiratory Tract Infection in Mexico
Sergio Vizcarra-Ugalde,Montserrat Rico-Hernández,César Monjarás-Ávila,Sofía Bernal-Silva,Maria E. Garrocho-Rangel,Uciel R. Ochoa-Pérez,Daniel E. Noyola +6 more
TL;DR: The ICU admission rate and mortality rate in Mexican infants hospitalized with RSV infection were 5.2% and 1%, respectively, which was higher in infants <6 months of age than in other age groups.
Journal ArticleDOI
Respiratory syncytial virus A genotype classification based on systematic intergenotypic and intragenotypic sequence analysis.
Juan Carlos Muñoz-Escalante,Andreu Comas-García,Sofía Bernal-Silva,Carla Daniela Robles-Espinoza,Guillermo Gómez-Leal,Daniel E. Noyola +5 more
TL;DR: A phylogenetic analysis of 4,353 RSV-A G gene ectodomain sequences and the results indicate that previously reported genotypes can be classified into nine distinct genotypes: GA1-GA7, SAA1, and NA1.
Phylogenomics and population genomics of SARS-CoV-2 in Mexico during the pre-vaccination stage reveals variants of interest B.1.1.28.4 and B.1.1.222 or B.1.1.519 and the nucleocapsid mutation S194L associated with symptoms.
Francisco Barona-Gómez,Luis Delaye,Erik Díaz-Valenzuela,Fabien Plisson,Arely Cruz-Pérez,Mauricio Díaz-Sánchez,Christian A. García-Sepúlveda,Alejandro Sanchez-Flores,Rafael Pérez-Abreu,Francisco J Valencia-Valdespino,Natali Vega-Magaña,José Francisco Muñoz-Valle,Octavio Patricio García-González,Sofía Bernal-Silva,Andreu Comas-García,Angélica Cibrián-Jaramillo +15 more
TL;DR: A real-time quantitative PCR screening and phylogenomic reconstructions directed at sequence/structure analysis of the spike glycoprotein revealed mutation of concern E484K in genomes from central Mexico, in addition to the nationwide prevalence of the imported variant 20C/S:452R (B.1.28.4) and 20B/P.