T
T. M. Jessell
Publications - 2
Citations - 944
T. M. Jessell is an academic researcher. The author has contributed to research in topics: Stimulation & Substance P. The author has an hindex of 1, co-authored 2 publications receiving 940 citations.
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Journal ArticleDOI
Opiate analgesics inhibit substance P release from rat trigeminal nucleus.
T. M. Jessell,L. L. Iversen +1 more
TL;DR: It is reported here that opiate analgesics are able to suppress the stimulus-evoked release of SP, which may represent a mechanism for the direct spinal analgesic actions of opiates.
Journal ArticleDOI
Opiate analgesics inhibit substance P release from rat trigeminal nucleus
T. M. Jessell,L. L. Iversen +1 more
TL;DR: A strong case is made for a descending inhibitory raphe-spinal pathway in the DLF that mediates opiate and brain stimulation induced analgesia.