U
Urban Forsum
Researcher at Uppsala University
Publications - 73
Citations - 3142
Urban Forsum is an academic researcher from Uppsala University. The author has contributed to research in topics: Antigen & Antibody. The author has an hindex of 27, co-authored 73 publications receiving 3120 citations. Previous affiliations of Urban Forsum include Swedish University of Agricultural Sciences & Karolinska Institutet.
Papers
More filters
Journal ArticleDOI
Epidermal Langerhans cells express Ia antigens.
TL;DR: Which of the three cell types of epidermis, keratinocytes, melanocytes, and Langerhans cells, expresses the Ia antigens is investigated, and from the results of fluorescent antibody staining it is concluded that it is the LangerHans cells.
Journal ArticleDOI
Evidence in support of a self-perpetuating HLA-DR-dependent delayed-type cell reaction in rheumatoid arthritis.
TL;DR: It is shown that the large numbers of rheumatoid synovial HLA-DR-expressing macrophage-like/dendritic cells are heterogeneous and mediate either efficient activation or suppression of T-lymphocyte proliferation and a specific anti-collagen type II response is reported in three patients.
Journal ArticleDOI
Occurrence of Ia antigens on tissues on non-lymphoid origin
K. Wiman,Bengt Curman,Urban Forsum,Lars Klareskog,Ulla Malmnäs-Tjernlund,Lars Rask,L Trägårdh,Per A. Peterson +7 more
TL;DR: Examination of several cryostat sections of guinea pig tissues for the presence of la antigens by indirect immunofluorescence found staining patterns that were reproducible and significantly different from the controls it proved necessary to use immunosorbent-purified heteroantibodies.
Journal ArticleDOI
Relationships between HLA‐DR‐expressing Cells and T Lymphocytes of Different Subsets in Rheumatoid Synovial Tissue
TL;DR: An immunohistochemical double staining technique was used to study the relationships between HLA‐DR‐expressing, mostly macrophage‐like cells, and different populations of T lymphocytes in frozen sections of synovial tissue from patients with Inflammatory joint disease, particularly rheumatoid arthritis.
Journal ArticleDOI
Appearance of Anti‐HLA‐DR‐Reactive Cells in Normal and Rheumatoid Synovial Tissue
TL;DR: A role for synovial lining cells in HLA‐D‐locus‐dependent events of importance in the pathogenesis of rheumatoid arthritis and other joint diseases is suggested and the need for further investigations on T lymphocytes derived from the site of inflammation is pointed to.