A
A Berghout
Researcher at University of Amsterdam
Publications - 20
Citations - 2385
A Berghout is an academic researcher from University of Amsterdam. The author has contributed to research in topics: Graves' ophthalmopathy & Thyroid. The author has an hindex of 15, co-authored 20 publications receiving 2267 citations.
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Journal ArticleDOI
Clinical criteria for the assessment of disease activity in Graves' ophthalmopathy: a novel approach.
Maarten P. Mourits,Leo Koornneef,Wilmar M. Wiersinga,Mark F. Prummel,A Berghout,R van der Gaag +5 more
TL;DR: A retrospective study testing the efficacy of this classification found that patients with an activity score of 3 or more at the beginning of therapy responded well to anti-inflammatory drugs, while those with a lower activity score mostly did not.
Journal ArticleDOI
Prednisone and Cyclosporine in the Treatment of Severe Graves' Ophthalmopathy
Mark F. Prummel,Maarten Ph. Mourits,A Berghout,Eric P. Krenning,R van der Gaag,Leo Koornneef,Wilmar M. Wiersinga +6 more
TL;DR: It is concluded that single-drug therapy with prednisone is more effective than cyclosporine in patients with severe Graves' ophthalmopathy and the combination can be effective in patients who do not respond to either drug alone.
Journal ArticleDOI
Randomized double-blind trial of prednisone versus radiotherapy in Graves' ophthalmopathy.
TL;DR: Radiotherapy and oral prednisone appear to be equally effective as initial treatment in patients with moderately severe Graves' ophthalmopathy, and radiotherapy should be considered the treatment of first choice.
Journal ArticleDOI
Effect of abnormal thyroid function on the severity of Graves' ophthalmopathy.
Mark F. Prummel,Wilmar M. Wiersinga,Maarten Ph. Mourits,Leo Koornneef,A Berghout,R van der Gaag +5 more
TL;DR: The findings suggest that meticulous control of thyroid function also during antithyroid treatment is important in the management of Graves' ophthalmopathy.
Journal ArticleDOI
Determinants of thyroid volume as measured by ultrasonography in healthy adults in a non-iodine deficient area.
TL;DR: It is concluded that the sex difference in thyroid volume is due to the difference in body weight between males and females, and Lean body mass is presumably the most important physiological determinant of thyroid size in subjects living in a non‐iodine deficient area.