Nutrient and immunity transfer from cow to calf pre- and postcalving.

Regulation of calcium and phosphorus homeostasis in the dairy cow

The Physiology of Human Pregnancy

Scottish Blackface ewes were used to investigate the effect of protein deficiency during pregnancy on serum albumin, globulin, transferrin and plasma urea concentrations. Twenty-eight sheep were offered one of two iso-caloric diets in amounts which maintained energy intake at levels comparable to those found in hill sheep during winter. For half of the sheep (HP group) the crude-protein concentration was 11·8% and for the remainder (LP group) 6·0% in the dry matter. A further six sheep (group CL) were offered a diet containing 16·0% crude protein in amounts which prevented undernutrition. Concurrent changes in plasma volume and in certain serum proteins during pregnancy were determined in a second experiment.Serum globulins were not affected by protein intake and fell from 44·5 to 30·7 mg/ml during pregnancy. This was attributed mainly to a 30% increase in plasma volume which occurred during pregnancy.Serum albumin concentrations at the end of pregnancy were 29·3, 22·0 and 17'7 mg/ml and serum transferrin concentrations 400, 307 and 300 mg/100 ml in the CL, HP and LP groups respectively. Initial mean albumin and transferrin concentrations were 28·0 mg/ml and 383 mg/100 ml respectively. The usefulness of the parameters as indices of the protein status of pregnant ewes was discussed.Plasma urea N concentrations were related to the current protein intake of the animal. Mean values during late pregnancy were 26·0, 7'4 and 4·0 mg urea N/100 ml in the CL, HP, and LP) groups respectively. Limitations as to its usefulness were discussed.

Effects of dietary deficiencies of energy, protein and calcium on the pregnant ewe: IV. Serum total protein, albumin, globulin, transferrin and plasma urea levels

Calcium and phosphorus metabolism in ruminants with special reference to parturient paresis.

The effects of low protein and low Ca intakes during pregnancy on lamb composition and mineral contents have been investigated. Twenty-eight 6½-year-old Blackface ewes were used in a 2 × 2 experiment in which semi-purified diets containing 11·8 and 6·0% crude protein and 1·2 and 0·11 % Ca in the dry matter were offered to maintain constant levels of non-esterified fatty acids (NEFA) and ketone bodies in the plasma, comparable to those found in hill sheep in winter. A further group, control, were fed a conventional diet containing adequate crude protein and Ca to maintain NEFA and ketone body levels typical of well-nourished sheep. The lambs were killed at birth and whole body fat, moisture, nitrogen, Ca, P, Mg, Na and K contents determined. Further data was obtained on the brain, liver and semitendinosus muscle. Within the context of the experiment the most important factor in determining the mineral content of the lambs was the protein intake of the ewe, mainly due to its effect on lamb body weight. The mean Ca content of lambs from the control ewes was 47·8 g. By comparison that of lambs from the high and low protein groups was reduced by 4·9 and 12·9 g respectively. Calcium intakes as low as 27 mg/kg ewe body weight/day had no significant effect on lamb birth weight or mineral composition. The mean concentrations (g/kg) of minerals in the fat-free bodies of the lambs ranged from 12·1 to 14·6 for Ca, 6·6 to 7·4 for P, 0·49 to 006 for Mg and from 1·9 to 1·6 for K in the control and double deficiency groups respectively. It was concluded that these changes in lamb composition could be interpreted according to classical studies on the influence of undernutrition on the relative growth and development of animal tissues. The livers of the lambs, although significantly reduced in weight by the protein deficiency showed no evidence of being relatively more severely affected than muscle tissue.

A. C. Field

Papers

Effects of dietary deficiencies of energy, protein and calcium on the pregnant ewe. II. Body composition and mineral content of the lamb