The prevalence of squamous intraepithelial lesion is higher among human immunodeficiency virus (HIV)-positive women. These lesions when they occur in these patients are also more difficult to treat. A total of 205 consenting HIV-seropositive women were recruited. A cervical cytology (Pap smear) was taken, followed by visual inspection with freshly prepared 5% acetic acid and cervical biopsy taken from the squamocolumnar junction as the reference for diagnosis to avoid verification bias. The sensitivity of VIA was 76.0% (95% CI 52.0-91.0); specificity 83.0% (95% CI 77.0-88.0); positive predictive value 34.0% (95% CI 21.0-49.0). The sensitivity of cervical cytology (Pap smear) was 57.0% (95% CI 34.0-77.0), specificity of 95.0% (95% CI 90.0-97.0), and positive predictive value of 55.0% (95% CI 33.0-75.0). In HIV-seropositive women, the sensitivity of VIA is 76.0%, making it a useful screening test for preinvasive lesion of the cervix in low resource settings.

Correlation of cervical cytology and visual inspection with acetic acid in HIV-positive women

/pdf/celulas-de-langerhans-no-colo-uterino-de-mulheres-hiv-ftkal4o5dv.pdf

Células de Langerhans no colo uterino de mulheres HIV soropositivas com neoplasia intraepitelial cervical

Sexually transmitted diseases (STDs) have long been known, but they have only recently been recognized as causes of significant long-term morbidity, mainly as a result of increased knowledge concerning viral STDs. The relationship of these diseases with conditions such as anogenital cancer and acquired immunodeficiency syndrome (AIDS) has made viral STDs an important issue in the healthcare of women and infants, and in reproductive health. The evolution of the AIDS pandemic is now characterized by growing differences between rich and poor nations. New diagnostic tools include rapid tests of blood, urine and saliva samples. New techniques, such as computerized cytology, have been developed for the diagnosis of human papillomavirus (HPV). Women infected with HIV are at a greater risk of being co-infected with HPV, and they are also more prone to the progression and persistence of HPV lesions. The herpes simplex virus presents high rates of co-infection with HIV, and it plays a particularly important role in increasing transmission rates of this virus.

/pdf/sexually-transmitted-viral-diseases-in-women-clinical-and-1po990s4gt.pdf

Sexually-transmitted viral diseases in women: clinical and epidemiological aspects and advances in laboratory diagnosis.

Purpose: To compare Papanicolaou (Pap) smear readings to visual inspection with acetic acid (VIA) findings among HIV-infected women in Phnom Penh, Cambodia. Methods: A total of 304 HIV-infected wom...

Comparing Visual Inspection with Acetic Acid to Cytology in Detection of Precancerous Lesions of the Cervix in HIV-Infected Cambodian Women.

https://www.gynecologiconcology-online.net/article/S0090-8258(05)00662-1/pdf

A.E Faúndes

Papers

Prevalence of cervical squamous intraepithelial lesions in women with HIV