A
A. J. van der Vlies
Publications - 1
Citations - 977
A. J. van der Vlies is an academic researcher. The author has an hindex of 1, co-authored 1 publications receiving 878 citations.
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Journal Article
Exploiting lymphatic transport and complement activation in nanoparticle vaccines
Sai T. Reddy,A. J. van der Vlies,Eleonora Simeoni,C. P. O"neil,Melody A. Swartz,Jeffrey A. Hubbell +5 more
TL;DR: This work investigates whether nanoparticles can be used as a vaccine platform by targeting lymph node–residing dendritic cells via interstitial flow and activating these cells by in situ complement activation, and demonstrates generation of humoral and cellular immunity in mice in a size- and complement-dependent manner.