Pneumoconiosis, or occupational lung disease, is one of the world's most prevalent work-related diseases. Silicosis, a type of pneumoconiosis, is caused by inhaling respirable crystalline silica (RCS) dust. Although silicosis can be fatal, it is completely preventable. Hundreds of thousands of workers globally are at risk of being exposed to RCS at the workplace from various activities in many industries. Currently, in Australia and internationally, there are a range of methods used for the respiratory surveillance of workers exposed to RCS. These methods include health and exposure questionnaires, spirometry, chest X-rays, and HRCT. However, these methods predominantly do not detect the disease until it has significantly progressed. For this reason, there is a growing body of research investigating early detection methods for silicosis, particularly biomarkers. This literature review summarises the research to date on early detection methods for silicosis and makes recommendations for future work in this area. Findings from this review conclude that there is a critical need for an early detection method for silicosis, however, further laboratory- and field-based research is required.

https://www.mdpi.com/1660-4601/18/15/8123/pdf

Early Detection Methods for Silicosis in Australia and Internationally: A Review of the Literature.

Conformers of 1,2,3,4 –tetrahydroisoquinoline in S0 and S1: An analysis through potential energy surface, hardness principles and vibrational spectroscopy

Conformational landscape, stability, potential energy curves and vibrations of 1,2,3,4 tetrahydroquinoline

Investigation of the structures, potential energy surface, transition states and vibrational frequencies of a vitamin E precursor-chroman in S0 and S1 states: DFT based computational study

Conformer selective monohydrated clusters of 1,2,3,4 –tetrahydroisoquinoline in S0: I-Potential energy surface studies, vibrational signatures and NBO analysis

Abhijit Chakraborty

Papers

Conformers of 1,2,3,4 –tetrahydroisoquinoline in S0 and S1: An analysis through potential energy surface, hardness principles and vibrational spectroscopy

Fluorescence excitation spectra, Raman spectra and structure of isochroman in its S1 (π, π∗) state

Conformational landscape, stability, potential energy curves and vibrations of 1,2,3,4 tetrahydroquinoline

Investigation of the structures, potential energy surface, transition states and vibrational frequencies of a vitamin E precursor-chroman in S0 and S1 states: DFT based computational study

Conformer selective monohydrated clusters of 1,2,3,4 –tetrahydroisoquinoline in S0: I-Potential energy surface studies, vibrational signatures and NBO analysis