https://www.cell.com/trends/biotechnology/pdf/S0167-7799(16)00044-5.pdf

Metabolic Burden: Cornerstones in Synthetic Biology and Metabolic Engineering Applications

Methods may be provided to forward data packets to a plurality of servers with each server being identified by a respective server identification (ID). A non-initial data packet of a data flow may be received, with the non-initial data packet including information for the data flow, and a bucket ID for the non-initial data packet may be computed as a function of the information for the data flow. Responsive to the bucket ID for the data packet mapping to first and second server identifications (IDs) of respective first and second servers and responsive to the non-initial data packet being a non-initial data packet for the data flow, the non-initial data packet may be transmitted to one of the first and second servers using one of the first and second server IDs based on a flow identification of the data flow being included in a transient table for the bucket ID.

Methods of forwarding data packets using transient tables and related load balancers

A first data packet of a data flow may be addressed to a primary address and include information for the data flow and a bucket ID may be computed based on the information. Responsive to the bucket ID mapping to first and second servers and the first data packet being addressed to the primary address, the first data packet may be transmitted to the first server. A second data packet may be received addressed to a stand-by address and including the information for the data flow, and a bucket ID may be computed based on the information with the bucket IDs for the first and second packets being the same. Responsive to the bucket ID for the second data packet mapping to first and second servers and the second data packet being addressed to the stand-by address, the second data packet may be transmitted to the second server.

Methods of load balancing using primary and stand-by addresses and related load balancers and servers

In one embodiment, a method for load balancing in a software-define networking (SDN) system includes, upon receiving a packet, determining whether a matching entry for the packet in a server distribution table contains both a current and new server selection. If the matching entry contains both, it is determined whether there is a matching entry for the packet in a transient flow table, where the transient flow table maintains server selections when at least one of the plurality of servers is reconfigured. Upon determining that there is no matching entry for the packet in the transient flow table, the method determines whether the packet is a first packet of a traffic flow. If the packet is the first packet of a traffic flow, the packet is forwarded according to the new server selection of the matching entry in the server distribution table, and the transient flow table is updated.

Method and system for load balancing in a software-defined networking (sdn) system upon server reconfiguration

http://web.stanford.edu/group/covert/publicationpdfs/DMacklin2014.pdf

The future of whole-cell modeling

Whole-cell models promise to greatly facilitate the analysis of complex biological behaviors. Wholecell model development requires comprehensive model organism databases. WholeCellKB (http:// wholecellkb.stanford.edu) is an open-source webbased software program for constructing model organism databases. WholeCellKB provides an extensive and fully customizable data model that fully describes individual species including the structure and function of each gene, protein, reaction and pathway. We used WholeCellKB to create WholeCellKBMG, a comprehensive database of the Gram-positive bacterium Mycoplasma genitalium using over 900 sources. WholeCellKB-MG is extensively crossreferenced to existing resources including BioCyc, KEGG and UniProt. WholeCellKB-MG is freely accessible through a web-based user interface as well as through a RESTful web service.

https://www.karrlab.org/static/doc/papers/Karr2013.pdf

WholeCellKB: model organism databases for comprehensive whole-cell models

A method, in one or more network elements that are in communication between clients that transmit packets and servers, of distributing the packets among the servers which are to process the packets. Stickiness of flows to servers assigned to process them is provided. A packet of a flow is received at a static first level packet distribution module. A group of servers is statically selected for the packet of the flow with the first level module. State that assigns the packet of the flow to the selected group of servers is not used. The packet of the flow is distributed to a distributed stateful second level packet distribution system. A server of the selected group is statefully selected with the second level system by accessing state that assigns processing of packets of the flow to the selected server. The packet of the flow is distributed to the selected server.

Two level packet distribution with stateless first level packet distribution to a group of servers and stateful second level packet distribution to a server within the group

Abhishek Arora

Papers

WholeCellKB: model organism databases for comprehensive whole-cell models

Two level packet distribution with stateless first level packet distribution to a group of servers and stateful second level packet distribution to a server within the group