A
Achim Raap
Publications - 1
Citations - 208
Achim Raap is an academic researcher. The author has contributed to research in topics: Carbohydrate metabolism & Glucagon-like peptide-1. The author has an hindex of 1, co-authored 1 publications receiving 191 citations.
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Hepatic and glucagon-like peptide-1–mediated reversal of diabetes by glucagon receptor antisense oligonucleotide inhibitors
Kyle W. Sloop,Julia Xiao-Chun Cao,Angela M. Siesky,Hong Yan Zhang,Diane M. Bodenmiller,Amy L. Cox,Steven J. Jacobs,Julie S. Moyers,Owens Rebecca Anne,Aaron D. Showalter,Martin B. Brenner,Achim Raap,Jesper Gromada,Brian R. Berridge,David Monteith,Niels Pørksen,Robert Mckay,Brett P. Monia,Sanjay Bhanot,Lynnetta Watts,M. Dodson Michael +20 more
TL;DR: Together, these studies identify a novel mechanism whereby GCGR inhibitors reverse the diabetes phenotype by the dual action of decreasing hepatic glucose production and improving pancreatic beta cell function.