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Aiguo Zhang
Researcher at University of California, Berkeley
Publications - 2
Citations - 173
Aiguo Zhang is an academic researcher from University of California, Berkeley. The author has contributed to research in topics: Binding site & Nicotinic agonist. The author has an hindex of 2, co-authored 2 publications receiving 168 citations.
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Journal ArticleDOI
Insect nicotinic acetylcholine receptor: conserved neonicotinoid specificity of [(3)H]imidacloprid binding site.
TL;DR: This study shows conserved neonicotinoid specificity of the [3H]IMI binding site in each of the four insect species examined.
Journal ArticleDOI
5-Azidoimidacloprid and an Acyclic Analogue as Candidate Photoaffinity Probes for Mammalian and Insect Nicotinic Acetylcholine Receptors
Shinzo Kagabu,Peter Maienfisch,Aiguo Zhang,Joaquin Granda-Minones,Joerg Haettenschwiler,Hartmut Kayser,Thomas Maetzke,John E. Casida +7 more
TL;DR: azido substituent in 1 and 2 increases the affinity 7-79-fold for rat brain and recombinant alpha4beta2 nAChRs while maintaining high potency on both insect nA ChRs (Drosophila and Myzus) (K(i)s 1-15 nM competing with [(3)H]imidacloprid).