A
Akbar Dorgalaleh
Researcher at Iran University of Medical Sciences
Publications - 152
Citations - 1477
Akbar Dorgalaleh is an academic researcher from Iran University of Medical Sciences. The author has contributed to research in topics: Factor XIII deficiency & Factor XIII. The author has an hindex of 19, co-authored 138 publications receiving 1095 citations. Previous affiliations of Akbar Dorgalaleh include Shahid Beheshti University & University of Tehran.
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Journal ArticleDOI
Blood coagulation factor XIII and factor XIII deficiency
TL;DR: Molecular analysis of patients with FXIIID revealed a wide spectrum of mutations, most frequently missense mutations in the FXIII-A subunit, with a few recurrent mutations observed worldwide.
Journal ArticleDOI
Clinical manifestations and management of life-threatening bleeding in the largest group of patients with severe factor XIII deficiency
Majid Naderi,Akbar Dorgalaleh,Shaban Alizadeh,Shadi Tabibian,Soudabeh Hosseini,Morteza Shamsizadeh,Taregh Bamedi +6 more
TL;DR: Fibrogammin P® is effective in the management of FXIII deficiency, and higher dose of this drug is safe and effective in neonates, and Trp187Arg is the most common mutation of FX III-A subunit in Iran.
Journal ArticleDOI
Factor XIII deficiency in Iran: A comprehensive review of the literature
Akbar Dorgalaleh,Majid Naderi,Maryam Hosseini,Shaban Alizadeh,Soudabeh Hosseini,Shadi Tabibian,Peyman Eshghi +6 more
TL;DR: A comprehensive review on different aspects of FXIIID in the Iranian population reveals that Sistan and Baluchestan Province has not only the highest number of patients with FXIIIDs in Iran but the highest global incidence of this condition.
Journal ArticleDOI
Morbidity and mortality in a large number of Iranian patients with severe congenital factor XIII deficiency
TL;DR: Among 317 Iranian patients with FXIIID, 145 cases experienced 166 CNS bleeds (CNSBs) that recurred in 21 cases and 49 deaths (15.4 %) were observed in these patients, which highlight the importance of early diagnosis and intensive health care among patients withFXIIID.
Journal Article
Effect of Thyroid Dysfunctions on Blood Cell Count and Red Blood Cell Indice
Akbar Dorgalaleh,M Mahmoodi,Bijan Varmaghani,F Kiani Node,O Saeeidi Kia,Sh Alizadeh,S H Tabibian,Taregh Bamedi,M Momeni,S Abbasian,Z Kashani Khatib +10 more
TL;DR: Evaluating effect of hypo & hyperthyroidism on blood cell count and RBC indices revealed statistically significant difference between two groups of patients in RBC count, MCH, M CHC, RDW, HB and HCT, but the difference was not significant for WBC and PLT counts and MCV