Showing papers by "Akira Suzuki published in 2003"
01 Jul 2003
TL;DR: A common and inexpensive protein, egg albumin, was applied to the solid-liquid separation or flocculation of diatomite to study the adsorption and flocculating ability of methylated eggalbumin.
Abstract: A common and inexpensive protein, egg albumin, was applied to the solid-liquid separation or flocculation of diatomite. Egg albumin was methylated in a 0.05 M HCl methyl alcohol solution at room temperature. About 90% of the carboxylic groups of egg albumin could be methylated within 24 h. The adsorption of egg albumin onto diatomite at pH 6.8 was remarkably enhanced by methylation. The adsorption constant of methylated egg albumin to diatomite at 30 degrees C was about 100-fold larger than that of native egg albumin; however, the adsorption constant of methylated egg albumin decreased to about 1/100 with temperature decreasing from 30 to 6 degrees C. The saturated adsorption amount of egg albumin was also increased by the methylation. The flocculating ability of methylated egg albumin was examined with a diatomite suspension at 6 and 30 degrees C in the pH range from pH 2 to 11. The diatomite suspension was effectively flocculated by the addition of small amounts of methylated egg albumin (only 0.5-1 wt% against diatomite) over a wide pH range from pH 3 to 10.
26 citations
TL;DR: Findings appear to be the first evidence that CD25(+)CD4(+)immunoregulatory T cells are altered in animal models, which naturally develop autoimmune diseases.
14 citations
TL;DR: Palladium-catalyzed reaction of 1-alkenylboronates with vinylic halides: (1Z,3E)-1-phenyl-1,3-octadiene.
Abstract: Palladium-catalyzed reaction of 1-alkenylboronates with vinylic halides: (1Z,3E)-1-phenyl-1,3-octadiene
intermediate: (E)-1-Hexenyl-1,3,2-benzodioxaborole.
reactant: 6.7 mL (60 mmol) of catecholborane
product: (1Z,3E)-1-phenyl-1,3-octadiene
Keywords:
addition, to CC;
alkenylation, C-alkenylation;
metalation reactions, boron;
metal-catalyzed reactions, palladium;
dichlorobis(triphenylphosphine)palladium(II), preparation;
sodium ethoxide solution, preparation
12 citations
TL;DR: In this article, the authors reported that mice lacking the catalytic subunit of PI(3)Kγ on 129J backgrounds develop invasive colorectal tumours, and they have observed this cancer phenotype in mouse lines derived from two different targeted embryonic stem-cell clones for at least two years.
Abstract: Nature 406, 897–902 (2000). In this Letter, we reported that mice lacking the catalytic subunit of PI(3)Kγ on 129J backgrounds develop invasive colorectal tumours. We have observed this cancer phenotype in mouse lines derived from two different targeted embryonic stem-cell clones for at least two years.
8 citations
TL;DR: Palladium(0)-catalyzed reaction of 9-alkyl-9-borabicycle cyclo[3.3.1]nonane with 1-bromo-1-phenylthioethene: 4-(3-cyclohexenyl)-2phenyl-thio-1 -butene as mentioned in this paper.
Abstract: Palladium(0)-catalyzed reaction of 9-alkyl-9-borabicyclo[3.3.1]nonane with 1-bromo-1-phenylthioethene: 4-(3-cyclohexenyl)-2-phenylthio-1-butene
intermediate: 1-bromo-1-phenylthioethene
product: 4-(3-cyclohexenyl)-2-phenylthio-1-butene
intermediate: 9-[2-(3-cyclohexenyl)ethyl]-9-BBN
Keywords:
addition, to CC;
coupling;
halogenation, bromination;
hydroboration;
metalation reactions, boron;
metal-catalyzed reactions, palladium;
1,5-cyclooctadiene;
potassium phosphate, aqueous solution, 3 M;
tetrahydrofuran;
bromine
7 citations
Journal Article•
3 citations
Journal Article•
TL;DR: It is suggested that edema of the optic pathway seems to be caused not only by craniopharyngioma but also other suprasellar lesions, and metastasis should be kept in mind as a differential diagnosis, because of its various appearance in neuroimages.
Abstract: A rare case in presented of a patient with edema formation along the optic pathway, which was caused by metastatic suprasellar tumor mimicking craniopharyngioma. A 63-year-old female with visual disturbance, diabetes insipidus, and symptomatic panhypopituitarism was admitted to our hospital. CT images showed a suprasellar mass lesion. MR images demonstrated a heterogeneously enhanced tumor and edema along the optic nerve and tract. Although no cystic component is shown in radiological findings, these features are commonly observed in cases of craniopharyngioma. The patient underwent removal of the tumor by the transcranial approach. Since histological examination revealed adenocarcinoma, the tumor was diagnosed as metastatic brain tumor originating from non-recurrent rectal cancer operated on eight years previously. Conventional radiotherapy with a dose of 50GY was performed for the residual tumor. The tumor size was unchanged, but the edema had disappeared 7 months after the operation. Edema spreading along the optic tract was reported as a characteristic MR finding for diagnosis of craniopharyngiomas as distinguished from other common parasellar tumors. However, it is suggested that edema of the optic pathway seems to be caused not only by craniopharyngioma but also other suprasellar lesions. Even if there was a characteristic radiological finding for some specific diseases, metastasis should be kept in mind as a differential diagnosis, because of its various appearance in neuroimages.
3 citations