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Alain Daban

Researcher at University of Poitiers

Publications -  7
Citations -  3272

Alain Daban is an academic researcher from University of Poitiers. The author has contributed to research in topics: Chemoradiotherapy & Preoperative care. The author has an hindex of 6, co-authored 7 publications receiving 3021 citations.

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Chemotherapy with preoperative radiotherapy in rectal cancer

TL;DR: In patients with rectal cancer who receive preoperative radiotherapy, adding fluorouracil-based chemotherapy preoperatively or postoperatively has no significant effect on survival.
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Enhanced Tumorocidal Effect of Chemotherapy With Preoperative Radiotherapy for Rectal Cancer: Preliminary Results—EORTC 22921

TL;DR: In patients with rectal cancer, preliminary results of EORTC Trial 22921 indicate that the addition of CT to preop RT induces down-sizing, downstaging, and significant changes in histologic characteristics.
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Preoperative chemoradiotherapy versus preoperative radiotherapy in rectal cancer patients: assessment of acute toxicity and treatment compliance. Report of the 22921 randomised trial conducted by the EORTC Radiotherapy Group.

TL;DR: At the doses recommended in the protocol, the addition of 5-FU-LV to preoperative XRT slightly increased the amount of acute toxicity, however, the compliance with the radiation protocol or the feasibility of surgery did not decrease.
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Preoperative radiation (Preop RT) in rectal cancer: Effect and timing of additional chemotherapy (CT) 5-year results of the EORTC 22921 trial

TL;DR: A 2 x 2 factorial trial evaluates the addition of CT to preop RT and that of postop CT vs nil on overall survival and progression-free survival in patients with atypical central giant cell granuloma.
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Quality of surgery in T3-4 rectal cancer: Involvement of circumferential resection margin not influenced by preoperative treatment. Results from EORTC trial 22921

TL;DR: In this paper, risk factors for rectal cancer patients associated with circumferential resection margin (CRM) and number of examined lymph nodes (LN) and to correlate these parameters of surgical quality with local recurrence (LR), disease-free and overall survival (DFS and OS).