Alan R. Zinsmeister

TL;DR: It was concluded that mucosal antrectomy eliminated the gastrin-producing antral mucosa and, in combination with proximal gastric vagotomy, did not greatly alter gastric emptying of liquids or solids.

TL;DR: Yohimbine attenuates the increase in colonic tone after hyperventilation probably by enhancing inhibitory sympathetic input to the colon, and clonidine contributes to this effect through its role in modulating the tonic response.

TL;DR: In this paper, the authors present strategies for successful implementation and management of multisite clinical trials and knowledge gained through an international, multisite randomized clinical trial, including team composition, regulatory requirements, study organization and governance, communication strategies, recruitment and retention efforts, budget, technology transfer, and publication.

TL;DR: The population ≥65 years is rapidly increasing, but remarkably little is known about the natural history of abdominal pain with ageing.

TL;DR: The proposition of an antagonism between peptic ulcer and diabetes is not supported by the data and relative weight was the only significant predictor of the time to subsequent diabetes in a proportional hazards regression analysis.