Showing papers by "Aleš Linhart published in 2003"

Interventional treatment of multiple vascular involvement in young male with heterozygous familial hypercholesterolemia.

Abstract: We report a case of 31 year old man with heterozygous familial hypercholesterolemia and excessive tobacco use leading to acute myocardial infarction as the first manifestation of premature atherosclerosis. The patvent was treated by primary PTCA of occluded first marginal artery and at this time an attempt of recanalisation of occluded LAD was unsuccessful. The patient was referred for mini coronary bypass graft of the LIMA to LAD. During evaluation of carotid arteries we found a significant stenosis of the left internal carotid artery and occlusion of the left subclavian artery which made the use of LIMA unsuitable. Therefore, another attempt of PTCA of the occluded LAD was performed, this time with success. Hence PTA of the occluded subclavian artery was performed with good result. The patient was treated with the standard therapy of CAD and combined lipid lowering agents with significant reduction of plasma cholesterol. However, 2 years after the first MI, he suddenly died after swimming at the age of 31. In this patient the risk of premature CAD was increased by the presence of another powerful risk factor--the excessive tobacco use. Acute physical exercise probably acted as a trigger of acute coronary events at the time of both MI. Interventional methods were very effective in the treatment of multiple atherosclerotic lesions in this patient and provided significant relief of symptoms. Treatment of heterozygous FH is briefly discussed in this article.

Severe acute mitral regurgitation complicating acute myocardial infarction: case for aggressive therapy

Abstract: The mortality of patients with cardiogenic shock (CS) following acute myocardial infarction (AMI) remains high, despite modern reperfusion strategies. The progressive hemodynamic deterioration in patients with AMI is usually caused by left ventricular systolic dysfunction as a consequence of necrosis or ischaemia. The special subset of CS patients comprises patients with mechanical complications, mainly the severe acute mitral regurgitation (SAMR), ventricular septal and free wall rupture (8%, 6% and 2.7%, respectively, of all CS patients).

Serum cardiac markers response to biphasic compared with monophasic electrical cardioversion

Abstract: Defibrilation or cardioversion in critically ill cardiac patients may be followed by serum cardiac marker elevation. However, only few studies with limited patient samples assessing electrical myocardial injury have been published [1,2]. The aim of our study was to evaluate the response of serum cardiac markers following elective cardioversion for supraventricular tachyarrhyth-mias (SVT) and to analyze the impact of type of shock waveform.