Alexandre Kerkis

TL;DR: In vivo transplantation of immature dental pulp stem cells into immunocompromised mice, they showed dense engraftment in various tissues and the relative ease of recovery and the expression profiles of various markers justify further exploration of IDPSC for clinical therapy.

TL;DR: Corneal transparency of the rabbit eyes that underwent hIDPSC transplantation was improved throughout the follow-up, while the control corneas developed total conjunctivalization and opacification, and transplantation of a tissue-engineered h IDPSC sheet was successful for the reconstruction of corneal epithelium in an animal model of LSCD.

TL;DR: The findings suggest that hDPSC is an additional cell resource for correcting large cranial defects in rats and constitutes a promising model for reconstruction of human large cranIAL defects in craniofacial surgery.

TL;DR: It was shown that hIDPSC presented significant engraftment in GRMD dog muscles, although human dystrophin expression was modest and limited to several muscle fibers, which suggested that systemic multiple deliveries seemed more effective than local injections.

TL;DR: The data suggest that ES cells with XY chromosomes can produce under the same experimental conditions both types of presumptive gametes, and this production depends on their positional and temporal information within the EB context.