A
Alisdair I. Orr
Publications - 1
Citations - 1197
Alisdair I. Orr is an academic researcher. The author has contributed to research in topics: DNA repair & DNA damage. The author has an hindex of 1, co-authored 1 publications receiving 1146 citations.
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Identification and characterization of a novel and specific inhibitor of the ataxia-telangiectasia mutated kinase ATM.
Ian Hickson,Yan Zhao,Caroline Richardson,Sharon J. Green,Niall M. B. Martin,Alisdair I. Orr,Philip Michael Reaper,Stephen P. Jackson,Nicola J. Curtin,Graeme C. M. Smith +9 more
TL;DR: KU-55933 is a novel, specific, and potent inhibitor of the ATM kinase, which did not potentiate the cytotoxic effects of ionizing radiation on ataxia-telangiectasia cells, nor did it affect their cell cycle profile after DNA damage.