Medicinal chemistry and pharmacology of genus Tripterygium (Celastraceae).

A comparative study on the antinociceptive and anti-inflammatory activities of five Juniperus taxa

Upper Cretaceous amber from the Raritan Formation (Sayerville, New Jersey) has been investigated by Pyrolysis-GC-MS and Pyrolysis-GC-matrix isolation FTIR-MS. Results establish the existence of two distinct forms of amber in this deposit. Both forms are Class Ib ambers, but they are unambiguously differentiated on the basis of their (intact) diterpenoid composition. The presence of callitrisate in both forms, and cupraene in samples designated form 1, strongly suggest that both derive from related-but-distinct species within the Cupressaceae. In addition to callitrisate, dehydroabietate and analogous 17-nor-, 16,17-dinor- and 15,16,17-trinor- analogues of these compounds are also observed. The distributions of these products in multiple samples suggest that they are the result of biological emplacement, rather than diagenetic modification of the parent compounds. This indicates that the distributions of diterpenes observed in these samples are representative of the original bioterpenoids and, hence, are useful for chemotaxonomic analyses.

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The nature and fate of natural resins in the geosphere. XII. Investigation of C-ring aromatic diterpenoids in Raritan amber by pyrolysis-GC-matrix isolation FTIR-MS

Terpenoids from Juniperus polycarpus var. seravschanica

Molecular composition and chemotaxonomic aspects of Eocene amber from the Ameki Formation, Nigeria

Activity-directed study of Juniperus polycarpos led to the isolation of active antimicrobial viz., hinokiol, sandaracopimaric acid 4-eniabietic acid, and other minor terpenes in addition to sabinic acid. The antiinflammatory activity of hinokiol was also demonstrated, using carrageenan-induced inflammation_in rats. The structures of the isolated terpenes were determined by 1HNMR, 13CNMR and 2DNMR, APT, DEPT, PND spectra.

https://zjps.journals.ekb.eg/article_184815_126e667cec36da516e79772015709707.pdf

Aly El-Sayed

Papers

Diterpene constituents of juniperus polycarpos and their antimicrobial and anti-inflammatory activities

Genetic Variability, Combining Ability, Gene Action and Superiority for New White Maize Inbred Lines (Zea mays L.)