Amanda dos Santos Cavalcanti

TL;DR: In this article, the authors describe impairment on mRNA cytokine expression in leishmania infected dogs with high parasite load associated with a structural modification in the splenic lymphoid micro-architecture.

TL;DR: It is demonstrated that primary osteosarcoma cells are resistant to methotrexate treatment and sensitive to cisplatin and doxorubicin in vitro, and these observations may provide an explanation for the poor response of osteOSarcomas to chemotherapy.

TL;DR: This case warns to the suspicion of viscerotropic Leishmania in cases of chronic skin lesions and brings the discussion of the mechanisms involved in the parasite tissue tropism.

TL;DR: A TaqMan-based quantitative real time PCR (qPCR) assay was developed for specific detection and quantitation of L. infantum in tissue samples from experimentally or naturally infected animals, mice or dogs, respectively and detected a significantly higher parasite load in symptomatic than in the asymptomatic animals.

TL;DR: The visceral dissemination of L. braziliensis associated with systemic signs suggested that this co-infection could influence the parasite burden and disease progression.