A
András Polyák
Researcher at Hannover Medical School
Publications - 33
Citations - 613
András Polyák is an academic researcher from Hannover Medical School. The author has contributed to research in topics: Biodistribution & Translocator protein. The author has an hindex of 12, co-authored 31 publications receiving 498 citations. Previous affiliations of András Polyák include Curie Institute.
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Journal ArticleDOI
Absorption, Uptake and Tissue Affinity of High-Molecular-Weight Hyaluronan after Oral Administration in Rats and Dogs
Lajos Balogh,András Polyák,Domokos Máthé,Réka Király,Juliana Thuroczy,Marian Terez,Gyozo A. Janoki,Yaoting Ting,Luke R. Bucci,Alexander G. Schauss +9 more
TL;DR: Evidence for uptake and distribution to connective tissues of orally administered, high-molecular-weight HA and (99m)Tc-P is presented, showing an expected pattern of rapid absorption and excretion in urine, with accumulation in thyroid glands, stomach, kidney and bladder.
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177Lu-EDTMP: a viable bone pain palliative in skeletal metastasis.
Sudipta Chakraborty,Tapas Das,Sharmila Banerjee,Lajos Balogh,Pradip Chaudhari,Haladhar Dev Sarma,András Polyák,Domokos Máthé,Meera Venkatesh,Gyozoo Janoki,M. R. A. Pillai +10 more
TL;DR: The present study was oriented toward the preparation and biologic evaluation of 177Lu complex of ethylenediaminetetramethylene phosphonic acid (EDTMP) in various animal models, with an aim to prepare a viable radiopharmaceutical for bone pain palliation.
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Multispecies animal investigation on biodistribution, pharmacokinetics and toxicity of 177Lu-EDTMP, a potential bone pain palliation agent
Domokos Máthé,Lajos Balogh,András Polyák,Réka Király,Teréz Márián,Dariusz Pawlak,John Zaknun,M. R. A. Pillai,Győző Jánoki +8 more
TL;DR: The protracted effective half-life of ( 177)Lu-EDTMP in bone supports that modifying the EDTMP molecule by introducing (177)Lu does not alter its biological behaviour as a specific bone-seeking tracer.
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Nanoparticles for SPECT and PET Imaging: Towards Personalized Medicine and Theranostics.
András Polyák,Tobias L. Ross +1 more
TL;DR: This review takes a short historical look back to the radiocolloids, the great ancestors of (radiolabeled) nanoparticles and describes the general features of current types of PET and SPECT imaging associated nanoparticle-based products and key radiolabeling methods, entering into details of potential prospective challenges related to radiotheranostic approaches and imaging guided therapy.
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99mTc-labelled nanosystem as tumour imaging agent for SPECT and SPECT/CT modalities
András Polyák,István Hajdu,Magdolna Bodnár,György Trencsényi,Zita Pöstényi,Veronika Haász,Gergely Jánoki,Győző Jánoki,Lajos Balogh,János Borbély +9 more
TL;DR: The new nanoparticles as a targeted contrast agent improve tumour targeting and are able to detect folate-receptor-overexpressing tumours in animal models with enhanced contrast.