Showing papers by "Andrea Lemos published in 2015"

Cuffed versus uncuffed endotracheal tubes for general anaesthesia in children aged eight years and under

Abstract: Background Since the introduction of endotracheal intubation in paediatrics, uncuffed endotracheal tubes (ETTs) have been the standard of care for children under eight years old, based on the presumption that complications, particularly postoperative stridor, are higher with cuffed ETTs. The major disadvantages of uncuffed ETTs cited for this shift in procedure include the difficulty in achieving tidal volumes due to leakage around an uncuffed ETT. To seal the airway adequately, uncuffed tubes may need to be exchanged for another tube with a larger diameter, which sometimes requires several attempts before the appropriate size is found. Uncuffed tubes also allow waste anaesthetic gases to escape, contributing significantly to operating room contamination and rendering the anaesthetic procedure more expensive. Our review summarizes the available data, to provide a current perspective on the use of cuffed versus uncuffed endotracheal tubes in children of eight years old or less. Objectives To assess the risks and benefits of cuffed versus uncuffed endotracheal tubes during general anaesthesia in children up to eight years old. Search methods We searched CENTRAL, MEDLINE, Embase, CINAHL, LILACS and Google Scholar databases from their inception until March 2017. We also searched databases of ongoing trials, and checked references and citations. We imposed no restriction by language. Selection criteria We included randomized and quasi-randomized controlled trials in which the effects of using cuffed and uncuffed tubes were investigated in children up to eight years old undergoing general anaesthesia. We excluded studies conducted solely in newborn babies. Data collection and analysis We applied standard methodological procedures, as defined in the Methodological Expectations of Cochrane Intervention Reviews (MECIR). Main results We included three trials (2804 children), comparing cuffed with uncuffed ETTs. We rated the risks of bias in all three trials as high. Outcome data were limited. The largest trial was supported by Microcuff GmbH, who provided the cuffed tubes used. The other two trials were small, and should be interpreted with caution. Based on the GRADE approach, we rated the quality of evidence as low to very low. Two trials comparing cuffed versus uncuffed ETTs found no difference between the groups for postextubation stridor (risk ratio (RR) 0.93, 95% confidence interval (CI) 0.65 to 1.33; 2734 children; quality of evidence very low). However, those two trials demonstrated a statistically significantly lower rate of endotracheal tube exchange in the cuffed ETT group (RR 0.07, 95% CI 0.05 to 0.10; 2734 children; quality of evidence very low). One trial with 70 participants found that costs per case were lower in the cuffed ETT group (mean difference (MD) EUR 19.0 lower; 95% CI 24.23 to 13.77 lower; quality of evidence low), since the higher cost of the cuffed tubes may be offset by the savings made with anaesthetic gases. No clear evidence emerged to suggest any difference between cuffed and uncuffed tubes for outcomes such as the need to treat postextubation stridor with tracheal re-intubation (RR 1.85, 95% CI 0.17 to 19.76; 115 children; 2 trials; quality of evidence very low), epinephrine (RR 0.70, 95% CI 0.38 to 1.28; 115 children; 2 trials; quality of evidence very low) or corticosteroid (RR 0.87, 95% CI 0.51 to 1.49; 102 children; 1 trial; quality of evidence very low), or need for intensive care unit (ICU) admission to treat postextubation stridor (RR 2.77, 95% CI 0.30 to 25.78; 102 children; 1 trial; quality of evidence very low). None of the trials included in this review evaluated the ability to deliver appropriate tidal volume. Authors' conclusions Implications for practice We are unable to draw definitive conclusions about the comparative effects of cuffed or non-cuffed endotracheal tubes in children undergoing general anaesthesia. Our confidence is limited by risks of bias, imprecision and indirectness. The lower requirement for exchange of tubes with cuffed ETTs was very low-quality evidence, and the requirement for less medical gas used and consequent lower cost was low-quality evidence. In some cases, tracheal re-intubation is required to guarantee an open airway when adequate oxygenation is difficult after removal of the tube, for a variety of reasons including stridor, muscle weakness or obstruction. No data were available to permit evaluation of whether appropriate tidal volumes were delivered. Implications for research Large randomized controlled trials of high methodological quality should be conducted to help clarify the risks and benefits of cuffed ETTs for children. Such trials should investigate the capacity to deliver appropriate tidal volume. Future trials should also address cost effectiveness and respiratory complications. Such studies should correlate the age of the child with the duration of intubation, and with possible complications. Studies should also be conducted in newborn babies. Future research should be conducted to compare the effects of the different types or brands of cuffed tubes used worldwide. Finally, trials should be designed to perform more accurate assessments and to diagnose the complications encountered with cuffed compared to uncuffed ETTs.

Postural control assessment in students with normal hearing and sensorineural hearing loss.

Abstract: INTRODUCTION: Children with sensorineural hearing loss can present with instabilities in postural control, possibly as a consequence of hypoactivity of their vestibular system due to internal ear injury.OBJECTIVE: To assess postural control stability in students with normal hearing (i.e., listeners) and with sensorineural hearing loss, and to compare data between groups, considering gender and age.METHODS: This cross-sectional study evaluated the postural control of 96 students, 48 listeners and 48 with sensorineural hearing loss, aged between 7 and 18 years, of both genders, through the Balance Error Scoring Systems scale. This tool assesses postural control in two sensory conditions: stable surface and unstable surface. For statistical data analysis between groups, the Wilcoxon test for paired samples was used.RESULTS: Students with hearing loss showed more instability in postural control than those with normal hearing, with significant differences between groups (stable surface, unstable surface) (p < 0.001).CONCLUSIONS: Students with sensorineural hearing loss showed greater instability in the postural control compared to normal hearing students of the same gender and age.

Accuracy of the Alberta Infant Motor Scale (AIMS) to detect developmental delay of gross motor skills in preterm infants: A systematic review

Abstract: Objective: To assess, through a systematic review, the ability of Alberta Infant Motor Scale (AIMS) to diagnose delayed motor development in preterm infants. Methods: Systematic searches identified five studies meeting inclusion criteria. These studies were evaluated in terms of: participants’ characteristics, main results and risk of bias. The risk of bias was assessed with the Quality Assessment of Diagnostic Accuracy Studies – second edition (QUADAS-2). Results: All five studies included a high risk of bias in at least one of the assessed fields. The most frequent biases included were presented in patient selection and lost follow up. All studies used the Pearson correlation coefficient to assess the diagnostic capability of the Alberta Infant Motor Scale. None of the assessed studies used psychometric measures to analyze the data. Conclusion: Given the evidence, the research supporting the ability of Alberta Infant Motor Scale to diagnose delayed motor development in preterm infants presents l...

Repercussion of pelvic girdle pain on pregnant women's functionality evaluated through the Brazilian version of the Pelvic Girdle Questionnaire (PGQ-Brazil): a cross-sectional study

Abstract: | To analyze the impact of pelvic girdle pain on pregnant women’s functionality, a cross-sectional study involving pregnant women, aged between 18 and 30 years, with a clinical diagnosis of pregnancy-related pelvic girdle pain (PGPP) was performed. Clinical data were collected followed by the application of the Brazilian version of the Pelvic Girdle Questionnaire (PGQ-Brazil). One hundred and five pregnant women participated, of which 62.9% were multiparous. The most frequent diagnostic was the unilateral sacroiliac syndrome. About the onset of pain, 45.7% of them reported that pain occurred on movement and the activities that had greater limitation were sitting, standing, and walking for more than 60 minutes. The average pain according to the Visual Analog Scale (VAS) was 6.59 (SD 1.8), considered a moderate pain. Pregnant women with pelvic girdle syndrome had a mean of 54.86 (SD 22.39) for the total score of PGQ-Brazil; with unilateral sacroiliac syndrome, 31.11 (SD 17.37); and bilateral sacroiliac syndrome, 40.32 (SD 17.46). When the average pain was Barros et al. Repercussao da dor pelvica na funcionalidade de gestantes 405 compared among the groups assessed by the VAS, the pelvic girdle syndrome had the highest average pain (7.67; SD 1.72), followed by bilateral sacroiliac syndrome (6.86; SD 1.95), and the unilateral sacroiliac syndrome (6.21; SD 1.72). By correlating the average VAS with the total score of PGQ-Brazil, there was a positive correlation (r=0.458, p=0.01), indicating that the greater the pain, the greater the level of disability of the pregnant woman. The findings suggest that PGPP may result in different levels of disability, which may directly affect the pregnant women’s functionality.

Effects of transcranial direct current stimulation on motor learning in healthy individuals: a systematic review

Abstract: Introduction Transcranial direct current stimulation (tDCS) has been used to modify cortical excitability and promote motor learning. Objective To systematically review published data to investigate the effects of transcranial direct current stimulation on motor learning in healthy individuals. Methods Randomized or quasi-randomized studies that evaluated the tDCS effects on motor learning were included and the risk of bias was examined by Cochrane Collaboration’s tool. The following electronic databases were used: PubMed, Scopus, Web of Science, LILACS, CINAHL with no language restriction. Results It was found 160 studies; after reading the title and abstract, 17 of those were selected, but just 4 were included. All studies involved healthy, right-handed adults. All studies assessed motor learning by the Jebsen Taylor Test or by the Serial Finger Tapping Task (SFTT). Almost all studies were randomized and all were blinding for participants. Some studies presented differences at SFTT protocol. Conclusion The result is insufficient to draw conclusions if tDCS influences the motor learning. Furthermore, there was significant heterogeneity of the stimulation parameters used. Further researches are needed to investigate the parameters that are more important for motor learning improvement and measure whether the effects are long-lasting or limited in time.

Manual therapies for pain relief in patients with headache: a systematic review

Abstract: Objective. This systematic review aimed to assess the efficacy of manual therapies for headache relief. Method. A systematic search in MEDLINE, LILACS, Cochrane, CINAHL, Scopus and Web of Science databases was conducted for randomized and quasi-randomized trials, with no restrictions for language or year of publication. The de scriptors were ‘Headache’, ‘Headache disorders’ and ‘Musculoskeletal manipulations’, in addition to the keyword ‘Manual therapy’ and its equivalents in Portuguese. We included studies that compared massage, chiropractic manipulation, osteopathic manipulation and other spinal manipulation to groups with no intervention, other physiotherapeutic modalities or to a sham group. Results. Seven of the 567 articles initially screened were selected, including patients with tension type headache, cervicogenic headache or migraine. It was not possible to assess the magnitude of the treatment effect on the findings of this review. The main limitations were the absence of randomization and adequate allocation concealment, the lack of blinded evaluators and intention-to-treat analysis and inadequate statistical analysis. Conclusions. We were unable to determine the size of the treatment effect due to the selective description of findings. Owing to the high risk of bias in the articles included, the available evidence regarding the efficacy of manual therapies for headache relief is insufficient.

Cross-cultural adaptation of the Motor Assessment Scale (MAS) for Brazil

Abstract: Objetivo: Realizar a adaptacao transcultural da MAS para o Brasil. Metodo: O processo de adaptacao transcultural ocorreu em cinco estagios: 1) traducao da versao original da MAS por dois tradutores bilingues independentes; 2) sintese das traducoes (criacao da versao 1); 3) retrotraducao (a versao 1 em portugues foi revertida para o ingles por dois tradutores bilingues independentes); 4) analise do comite de especialistas (4 tradutores e dois fisioterapeutas); 5) pre-teste (aplicacao do instrumento na populacao alvo). Tambem foi realizado um estudo Delphi e o instrumento foi submetido a opiniao de 10 fisioterapeutas, de diferentes estados do Pais. Resultados: O consenso sobre a clareza, equivalencia semântica e relevância tecnico-cientifica da MAS foi obtido na segunda fase do estudo Delphi, com concordância entre 80 e 100%. Na primeira fase do estudo Delphi, foram dadas sugestoes para melhorar a clareza dos itens, que resultaram na lista Delphi 2. Conclusao: A MAS-Brasil foi criada atraves de um adequado processo de adaptacao transcultural, garantindo a sua equivalencia semântica e adequacao cultural. Ainda e necessario verificar as propriedades de medida desta versao para a sua adequada utilizacao clinica e em pesquisas

Manual therapies for pain relief in patients with headache: a systematic review Terapias manuais no alívio da dor em pacientes com cefaleia: uma revisão sistemática

Abstract: Objective. This systematic review aimed to assess the efficacy of manual therapies for headache relief. Method. A systematic search in MEDLINE, LILACS, Cochrane, CINAHL, Scopus and Web of Science databases was conducted for randomized and quasi-randomized trials, with no restrictions for language or year of publication. The de scriptors were ‘Headache’, ‘Headache disorders’ and ‘Musculoskeletal manipulations’, in addition to the keyword ‘Manual therapy’ and its equivalents in Portuguese. We included studies that compared massage, chiropractic manipulation, osteopathic manipulation and other spinal manipulation to groups with no intervention, other physiotherapeutic modalities or to a sham group. Results. Seven of the 567 articles initially screened were selected, including patients with tension type headache, cervicogenic headache or migraine. It was not possible to assess the magnitude of the treatment effect on the findings of this review. The main limitations were the absence of randomization and adequate allocation concealment, the lack of blinded evaluators and intention-to-treat analysis and inadequate statistical analysis. Conclusions. We were unable to determine the size of the treatment effect due to the selective description of findings. Owing to the high risk of bias in the articles included, the available evidence regarding the efficacy of manual therapies for headache relief is insufficient.