Andrew J. Daugulis

TL;DR: Methods to predict the biocompatibility and extractant capability of solvents are discussed and a computer program, known as the extractant screening program or ESP, has been developed to effectively predict the behavior of virtually any product in any solvent/aqueous system.

TL;DR: The use of a second, distinct, organic phase in a bioreactor has been shown to provide a virtually foolproof means of feeding substrate to cells because this process concept relies only on thermodynamic equilibrium and the cells' own rate of metabolism.

TL;DR: Exposure at a lower temperature increased the yield of the recombinant protein dramatically, which might be due to the enhanced protein folding pathway, as well as increased cell viability at lower temperature, and suggested that P. pastoris is a useful system for the production of soluble and biologically active herring antifreeze protein required for structural and functional studies.

TL;DR: Significant improvements in cell density and monoclonal antibody concentration were attributed to a lower (22%) intracapsular alginate content as well as better retention of the cell product by the modified capsule membrane.

TL;DR: An updated state-of-the-art review on the advances of TPPB technology for air pollution control, where the most recent insights regarding non-aqueous phase (NAP) selection, microbiology, reactor design, mathematical modeling and case studies are critically reviewed and discussed.